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Effects of Blood Transfusion on Cause-Specific Late Mortality After Coronary Artery Bypass Grafting—Less Is More  Thomas A. Schwann, MD, Joseph R. Habib,

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Presentation on theme: "Effects of Blood Transfusion on Cause-Specific Late Mortality After Coronary Artery Bypass Grafting—Less Is More  Thomas A. Schwann, MD, Joseph R. Habib,"— Presentation transcript:

1 Effects of Blood Transfusion on Cause-Specific Late Mortality After Coronary Artery Bypass Grafting—Less Is More  Thomas A. Schwann, MD, Joseph R. Habib, BS, Jawad M. Khalifeh, BS, Victor Nauffal, MD, Mark Bonnell, MD, Christopher Clancy, MD, Milo C. Engoren, MD, Robert H. Habib, PhD  The Annals of Thoracic Surgery  Volume 102, Issue 2, Pages (August 2016) DOI: /j.athoracsur Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Fifteen-year cumulative (cum.) incidence functions in coronary artery bypass graft surgery (CABG) patients compared for transfusion (Txn [red lines]) versus no-transfusion (NoTxn [black lines]) for (A) all-cause deaths, (B) cardiac mortality, and (C) noncardiac mortality. Analyses were done based on all patients (top panels) and repeated for patients having complications (middle panels) versus patients not having complications (bottom panels). All-cause death was cardiac plus noncardiac plus unknown-cause deaths; all pairwise comparisons were done by competing risks regression analysis. (HR = hazard ratio.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Forest plots showing transfusion (Txn) versus no-transfusion (NoTxn) 15-year mortality hazard ratio (HR) with 95% confidence interval (C.I.) for complicated (Compl [blue]), not complicated (No Compl [black]), and overall patient population (All PTS [gray]). (Left) Unadjusted HR (open symbols) and covariate-adjusted hazard ratio (AHR [closed symbols]) based on overall study cohort; (right) match-adjusted HR based on propensity matched patients only (HR <1 favors transfusion; HR >1 favors no transfusion). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions


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