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Wellcome Centre for Neuroimaging at UCL

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Presentation on theme: "Wellcome Centre for Neuroimaging at UCL"— Presentation transcript:

1 Wellcome Centre for Neuroimaging at UCL
Will Penny Wellcome Centre for Neuroimaging at UCL Methods Physics Attention Language Memory Emotion Vision fMRI MEG Theoretical Neurobiology

2 Statistical Parametric Mapping (SPM)
Image time-series Kernel Design matrix Statistical parametric map Realignment Smoothing General linear model Random Field Theory Statistical inference Normalisation p <0.05 Template Parameter estimates

3 Dynamic Models of Brain Interactions
Hemodynamic forward model: neural activityBOLD (nonlinear) Electric/magnetic forward model: neural activityEEG MEG LFP (linear) Neural state equation: fMRI MEG Neural model: 1 state variable per region bilinear state equation no propagation delays Neural model: 8 state variables per region nonlinear state equation propagation delays inputs

4 Dynamical Neural Network Model for fMRI
z1 z2 u1 a11 a22 c a12 a21 b21 u2 u1 z1 z2

5 Opportunities Computer Science UCL CoMPLEX Engineering Physics
Statistics UCL CoMPLEX


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