1. caFE Server Siteman Cancer Center

2. Introduction Annotate probes on microarrays using publicly available biomedical databases Automatically update annotations on a regular basis Web-based and API based query search Uses caCORE SDK (version 1.0.3) generated code Working towards caGRID compliance

3. Data Sources Entrez Gene UniGene Gene Ontology dbSNP UniSTS HomoloGene PubMed

4. Annotation Interlinks Microarrays CustomcaArray Entrez GeneUniGeneGenBank Accession NumberUniGene ClusterIDGene ID HomoloGenedbSNPPubMedGene Ontology Orthologus genesRefSNP IDPubmed relationship GO terms

5. Limitations Initial run of PubMed data curation takes 2-3 months APIs generated using caCORE SDK Not optimized for complex searches Performing searches that involves complex computations. For example, searching for literature correlation with depth 2 or more Meta-information of caArray is not stored

6. Demo