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Malassezia globosa and restricta: Breakthrough Understanding of the Etiology and Treatment of Dandruff and Seborrheic Dermatitis through Whole-Genome.

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Presentation on theme: "Malassezia globosa and restricta: Breakthrough Understanding of the Etiology and Treatment of Dandruff and Seborrheic Dermatitis through Whole-Genome."— Presentation transcript:

1 Malassezia globosa and restricta: Breakthrough Understanding of the Etiology and Treatment of Dandruff and Seborrheic Dermatitis through Whole-Genome Analysis  Thomas L. Dawson  Journal of Investigative Dermatology Symposium Proceedings  Volume 12, Issue 2, Pages (December 2007) DOI: /sj.jidsymp Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Relative composition of human sebum.
(reprinted from Ro and Dawson, 2005) Journal of Investigative Dermatology Symposium Proceedings  , 15-19DOI: ( /sj.jidsymp ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 A model of the role of Malassezia lipase-mediated hydrolysis of scalp lipids in the etiology of dandruff and seborrheic dermatitis. Some fatty acids are consumed by the fungal cells, whereas other fatty acids cause scalp irritation. (reprinted from DeAngelis et al., 2007) Journal of Investigative Dermatology Symposium Proceedings  , 15-19DOI: ( /sj.jidsymp ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions


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