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Meaghan O’Malley, MD, Amanda N. King, Marisa Conte, MLIS, Vicki L

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Presentation on theme: "Meaghan O’Malley, MD, Amanda N. King, Marisa Conte, MLIS, Vicki L"— Presentation transcript:

1 Effects of Cigarette Smoking on Metabolism and Effectiveness of Systemic Therapy for Lung Cancer 
Meaghan O’Malley, MD, Amanda N. King, Marisa Conte, MLIS, Vicki L. Ellingrod, PharmD, Nithya Ramnath, MBBS  Journal of Thoracic Oncology  Volume 9, Issue 7, Pages (July 2014) DOI: /JTO Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 PAH-induced direct (A) transcriptional and (B) epigenetic regulation of cytochrome P450 enzymes, CYP1A1, and CYP1A2. PAH, polycyclic aromatic hydrocarbon; Ah, aryl hydrocarbon; ARNT, aryl hydrocarbon receptor nuclear translocator; Hsp90, heat shock protein 90; XAP2, X-associated protein. Journal of Thoracic Oncology 2014 9, DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

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