1. The Role of Contrast-Enhanced Ultrasound in Guiding Radiofrequency Ablation of Hepatocellular Carcinoma 
Andy K.W. Chan, MD, FRCPC, Chris Hegarty, MB, BCh, BAO, FRCPC, Darren Klass, MD, PhD, FRCPC, Eric Yoshida, MD, MHSc, FRCPC, Stephen Chung, MD, PhD, FRCSC, David M. Liu, MD, FRCPC, FSIR, Stephen G.F. Ho, MD, FRCPC, Alison C. Harris, MBChB, MRCP, FRCR, FRCPC 
Canadian Association of Radiologists Journal 
Volume 66, Issue 2, Pages (May 2015)
DOI: /j.carj
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2. Figure 1
Utility of contrast-enhanced ultrasound (CEUS). Conventional B-mode US (left) demonstrates no definitive hepatic lesions in a background of heterogeneous hepatic parenchyma. CEUS (right) clearly demonstrates a hypervascular lesion during the arterial phase, consistent with HCC.
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
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3. Figure 2
Typical appearance of hepatocellular carcinoma on contrast-enhanced ultrasound. During arterial phase (left), the tumour demonstrates hypervascularity, with subsequent washout during portal venous and delayed phase imaging (right).
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
Copyright © 2015 Canadian Association of Radiologists Terms and Conditions

4. Figure 3
Patient A: Triphasic liver computed tomography demonstrates a lesion in segment 4A of the liver, hypervascular on arterial phase (left image) with washout on both portal venous (middle image) and delayed phases (right image).
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
Copyright © 2015 Canadian Association of Radiologists Terms and Conditions

5. Figure 4
Patient A: Contrast-enhanced ultrasound (CEUS) performed 1 month later confirms a hypervascular lesion in segment 4A of the liver (Figure 3). Radiofrequency ablation was then performed under CEUS guidance.
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
Copyright © 2015 Canadian Association of Radiologists Terms and Conditions

6. Figure 5
Patient A: Triphasic liver computed tomography at 6-month follow up demonstrates a hypervascular nodular focus within the segment 4A ablation zone, in keeping with recurrent disease (left image = arterial phase; middle image = portal venous phase; right image = delayed phase).
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
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7. Figure 6
Patient A: Contrast-enhanced ultrasound performed 1 week after the 6-month follow-up computed tomography (CT) (Figure 5) demonstrates the segment 4A recurrent disease, which closely resembles the appearance on CT (Figure 5).
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
Copyright © 2015 Canadian Association of Radiologists Terms and Conditions