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Figure 1 Time points of blood sampling

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1 Figure 1 Time points of blood sampling
Time points of blood sampling Alemtuzumab (blue line) was given on 5 consecutive days (day 1–day 5) within 4 hours. On days 1–3, patients were pretreated with methylprednisolone (red line) 1 hour before alemtuzumab infusion. Blood samples (B) were taken before methylprednisolone, after methylprednisolone, and after alemtuzumab infusion each of the 5 consecutive days. Vital signs (V) were evaluated hourly. Paracetamol (P) was given before each alemtuzumab infusion. Patients received concomitant medication (CM) including antihistaminergic treatment and acyclovir in the morning (M) and evening (E) of each day. Katja Thomas et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e228 © 2016 American Academy of Neurology


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