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Acute generalized exanthematous pustulosis induced by mifepristone

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Presentation on theme: "Acute generalized exanthematous pustulosis induced by mifepristone"— Presentation transcript:

1 Acute generalized exanthematous pustulosis induced by mifepristone
Brandon M. Kirsch, MD, Mark A. Cappel, MD  JAAD Case Reports  Volume 1, Issue 4, Pages (July 2015) DOI: /j.jdcr Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 AGEP. Diffuse erythematous eruption covered with several hundred superficial, nonfollicular pustules. Patient reported burning of the skin. Note confluence of pustules into lakes of pus. JAAD Case Reports 2015 1, DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Accentuation in the skin folds including the waistline, intergluteal cleft, and popliteal fossae. JAAD Case Reports 2015 1, DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Biopsy specimens reveal typical histologic features of acute generalized exanthematous pustulosis. Note subcorneal pustules with neutrophils and perivascular mixed inflammatory infiltrate. (Hematoxylin-eosin stain; original magnifications: ×4 [top], ×10 [middle], ×20 [bottom].) JAAD Case Reports 2015 1, DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Brisk perivascular infiltrate with many eosinophils and focal small-vessel vasculitis. (Hematoxylin-eosin stain; original magnifications: ×20 [top], ×40 [bottom].) JAAD Case Reports 2015 1, DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions


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