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What Does the Future Hold and What Will It Mean for Patients?

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Presentation on theme: "What Does the Future Hold and What Will It Mean for Patients?"— Presentation transcript:

1 What Does the Future Hold and What Will It Mean for Patients?

2

3 The Standard of Care is Changing Again

4 Why Do We Need a New Standard of Care?

5 The Ideal Treatment for Chronic HCV Infection

6 Agents in Phase 3 HCV Treatment Pipeline Not Approved for Use in the US

7 Sofosbuvir

8 VALENCE: Sofosbuvir + RBV for 24 Weeks in G3 HCV Infection

9 NEUTRINO Study: SVR12 by HCV Genotype

10 NEUTRINO Study: Virologic Response by Cirrhosis Status

11 Simeprevir in Patients With G1 HCV Infection

12 Shortened Therapy in 85% to 91%

13 Q80K: A Major Issue

14 On the Road to IFN-free Therapy

15 On the Road to IFN-free Therapy (cont)

16 One Size Fits All vs Tailored Regimen

17 Second-Generation Protease Inhibitor-based, IFN-free Regimens

18 PI + NS5A in Prior Null Responders

19 IFN-free Regimens Combining 3 DAA Drug Classes

20

21 More Potent Protease Inhibitors in Phase 2 Clinical Trials

22 What Does It Mean for Patients?

23 Abbreviations

24 Abbreviations (cont)

25 References

26 References (cont)

27 References (cont)


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