1. What are the different parts in the phospholipid bilayer?
Have out text book to Ch 3.3.
Have out CW packet to page 2.
Have out a different writing utensil than what you initially wrote in on page 2.

2. Cell membranes are composed of two phospholipid layers.
The cell membrane has two major functions.
forms a boundary between inside and outside of the cell
cell membrane
outside cell
inside cell

3. Cell membranes are composed of two phospholipid layers.
The cell membrane has two major functions.
forms a boundary between inside and outside of the cell
controls passage of materials
cell membrane
outside cell
inside cell

4. Cell membranes are composed of two phospholipid layers.
The cell membrane is made of a phospholipid bilayer.
cell membrane

5. Cell membranes are composed of two phospholipid layers.
The cell membrane is made of a phospholipid bilayer.
There are other molecules embedded in the membrane.
cell membrane
protein
cholesterol
carbohydrate
chain
protein channel

6. Cell membranes are composed of two phospholipid layers.
The cell membrane is made of a phospholipid bilayer.
There are other molecules embedded in the membrane.
The fluid mosaic model describes the membrane.
cell membrane
protein
cholesterol
carbohydrate
chain
protein channel

7. Cell membranes are composed of two phospholipid layers.
Proteins – integral (through the membrane) and peripheral (on the edge)
Involved in transport, signaling, communication, etc…
Carbohydrates – cell to cell recognition – think organ transplant
Lipids – make up bilayer and also are cholesterol which keeps membrane fluid

8. THE TLR receptors are part of the immune system which will recognize bacteria sequences that don’t belong!!!
THAT’S SIGNALING

9. The Endomembrane System
Nucleus (nuclear membrane)
Rough ER/Smooth ER
Golgi Apparatus
Vesicles
Lysosome
Cell Membrane
All of above have a membrane and are in some way connected – think protein

10. Cell membranes are composed of two phospholipid layers.
The cell membrane is selectively permeable.
Some molecules can cross the membrane while others cannot.

11. Cell membranes are composed of two phospholipid layers.
The cell membrane is selectively permeable.
Some molecules can cross the membrane while others cannot.

12. What happens when the cell membrane is faulty?
Diseases such as cystic fibrosis and protein deficiency in dysferlin can cause damage to your heart since you cannot repair the cell membrane that tear during exercise
Cystic fibrosis
Incorrect genetic instructions for a protein in your membrane that allows chloride ions out of your cells
Allows chloride ions to accumulate – leads to improper salt balance and build up of a sticky mucus esp in lungs
Can’t be moved out of the lungs so it collects and keeps the lungs from working the right way
Must receive treatment – often laying at an extreme slant and patting the chest and back to get the mucus to where they can cough it out
Life expectancy – 35 – 40 years or longer

14. Chemical signals are transmitted across the cell membrane.
Receptors bind with ligands and change shape.
There are two types of receptors.

15. Chemical signals are transmitted across the cell membrane.
Receptors bind with ligands and change shape.
There are two types of receptors.
intracellular receptor

16. Chemical signals are transmitted across the cell membrane.
Receptors bind with ligands and change shape.
There are two types of receptors.
intracellular receptor
membrane receptor

18. What needs to get done:
Pick up sheet as you come in.
Write down the homework.
Classwork pages 2 and 3
Keystone #1 and #2 – Due on Friday at the start of class.
You will have the rest of the period today and part of the period tomorrow to work on this. Tomorrow we will have a review activity of the cell membrane. Then you will have work time.

19. Complete the following question based upon the diagram below.
1. Which letter allows for cell to cell recognition?
2. Which letter allows for molecules to go in and out of the cell? What are they called?
3. Which letters are lipids?
4. Is the top or the bottom the outside of the cell? Explain
Complete the following question based upon the diagram below.

20. Have out keystone and CW packet so the top cover page is showing

21. Diagram of the cell membrane

22. Review of page 3:
A- phosopholipid bilayer: let in and out nonpolar molecules
B-phosopholipid
C- polar head: hydrophilic and faces in/out of cell in PLBL
D-fatty acid tails: hydrophilic, faces interior of PLBL
E-cholesterol: adds rigidness to PLBL for temp changes
F- Proteins: lets polar and big molecules in and out of cell
K- Carbohydrates: outside of cell for recognition

26. 3.4 Diffusion and Osmosis
KEY CONCEPT Materials move across membranes because of concentration differences.
Molecules naturally flow from an area of HIGH to LOW. This is called moving WITH the CONCENTRATION GRADIENT.

27. 3.4 Diffusion and Osmosis
Passive transport does not require energy input from a cell.
Molecules can move across the cell membrane through passive transport.
No energy required
Moving with concentration
gradient (high to low)
There are two types of passive transport.
diffusion
osmosis

28. 3.4 Diffusion and Osmosis
Diffusion and osmosis are types of passive transport.
Molecules diffuse down a concentration gradient.
What can you think of that diffuse?

30. 3.4 Diffusion and Osmosis
Diffusion and osmosis are types of passive transport.
Osmosis is the diffusion of water molecules across a semipermeable membrane.

32. 3.4 Diffusion and Osmosis
Diffusion and osmosis are types of passive transport.
There are three types of solutions.
isotonic
hypertonic
hypotonic

33. Pd. 1: Have out page 5 power notes

34. 3.4 Diffusion and Osmosis
Some molecules can only diffuse through transport proteins.
Some molecules cannot easily diffuse across the cell membrane.
Facilitated diffusion is diffusion through transport proteins.
Animation

35. KEY CONCEPT Cells use energy to transport materials that cannot diffuse across a membrane.

36. Active transport requires energy input from a cell and enables a cell to move a substance against its concentration gradient.
Passive transport requires no energy from the cell.
Active transport is powered by chemical energy (ATP).
Active transport occurs through transport protein pumps.
Cells use active transport to maintain homeostasis.

37. How does passive transport relate to us?
Laxatives and constipation
When you take milk of magnesia, it has magnesium salts in it which are not well absorbed.
This causes water to move by osmosis into the intestines
Soften feces
Relieves constipation
WHO KNEW!!

38. For the rest of the period:
Read chapter 3.4 and complete the remaining parts of power notes on page 5
Complete the concept map on page 6
Work on Keystone #1 that is due on Friday, if finished with pages 5 and 6.

39. Diffusion and Osmosis Lab
With your partner read pages 7 and 8 together.
Answer the questions on the bottom of page 8 – use your textbook and notes as a review. The only new term is active transport which we learn about next week.
You must complete page 9 with setting up your experiment. For the experiment, you will need a ruler, three gummy bears, and three dixie cups. Make sure you label your dixie cups with your name and your partner’s name.
Place your cups in the open cabinet towards the front of the room when you are done.

40. Chemistry
Place homework in the HW bin.
Finish up Mole Lab
Make sure to have calculator, mole map and periodic table.
When you are finished mole lab complete CW assignment #2. Finish up CW #2 over the weekend.

41. Finish Gummy bear lab
Have out keystone assignment #1
Get your experiment from yesterday and a ruler.
When measurements are done rinse out cups nd scrub out. Place on dry rack.
Take the first 8 minutes of class to record your observation in the data chart on page 10 of your classwork packet. Then complete #7. Clean up – throw gummies away, rinse out cups and place them on dry rack!
If you get done this before our class conservation, complete the rest of the lab… pages 11 and 12 in the CW packet.
For the rest of class, finish CW pages 11 and 12. If you get this done… complete HW packet.

42. KEY CONCEPT Cells use energy to transport materials that cannot diffuse across a membrane.

43. Active transport requires energy input from a cell and enables a cell to move a substance against its concentration gradient.
Passive transport requires no energy from the cell.
Active transport is powered by chemical energy (ATP).
Active transport occurs through transport protein pumps.
Cells use active transport to maintain homeostasis.

44. Animation

45. A cell can import and export large materials or large amounts of material in vesicles during the processes of endocytosis and exocytosis.
Cells use energy to transport material in vesicles.
Endocytosis is the process of taking material into the cell.
Phagocytosis is a type of endocytosis.

46. A cell can import and export large materials or large amounts of material in vesicles during the processes of endocytosis and exocytosis.
Cells use energy to transport material in vesicles.
Exocytosis is the process of expelling material from the cell.

48. SO what moves across the membrane and how?
Type of Transport
Passive/active
How it works
Example
Diffusion
Passive
High to low, across membrane
Small, nonpolar
CO2, O2
Osmosis
High to low, uses a special protein
Water
Facilitated Diffusion
High to low, carrier or channel protein
Large, polar
Glucose, Cl-
Active Transport
Active
Low to high, carrier protein
Sodium Potassium Pump
Endocytosis
Engulfed by the membrane
Bacteria, fluid from outside the cell
Exocytosis
Released by the membrane
Waste and such from inside the cell