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Efficacy and Safety of a Magnesium Sulfate–Rich Natural Mineral Water for Patients With Functional Constipation  Christophe Dupont, Alain Campagne, Florence.

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Presentation on theme: "Efficacy and Safety of a Magnesium Sulfate–Rich Natural Mineral Water for Patients With Functional Constipation  Christophe Dupont, Alain Campagne, Florence."— Presentation transcript:

1 Efficacy and Safety of a Magnesium Sulfate–Rich Natural Mineral Water for Patients With Functional Constipation  Christophe Dupont, Alain Campagne, Florence Constant  Clinical Gastroenterology and Hepatology  Volume 12, Issue 8, Pages (August 2014) DOI: /j.cgh Copyright © 2014 AGA Institute Terms and Conditions

2 Figure 1 Flow chart of the patients.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

3 Figure 2 (A) Proportion of responders in each group and at each evaluation period (FAS population) (B) according to the Mg2+ and SO42- osmolarity of the treatment at each evaluation period (FAS population). Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

4 Figure 3 Change in stool consistency from baseline to week 2 (Bristol scale, FAS population). Types I and II, hard or lumpy stool; types III through V, normal stool; types VI and VII, loose to liquid stool. *P < .05. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

5 Figure 4 Evolution of the Rome III score according to the baseline level of abdominal pain (VAS scale, 0–100 mm) (FAS population). Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

6 Figure 5 Use of rescue medication (ie, macrogol 4000) (FAS population). *P < .05; ***P < .001. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions


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