1. Can Measures of Coronary Dynamics Explain Chest Pain Without Coronary Artery Disease? 
Richard O. Cannon, M.D. 
Mayo Clinic Proceedings 
Volume 73, Issue 12, Pages (December 1998)
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Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Fig. 1
Scatterplot showing absence of association between maximal increase in coronary blood flow (CBF) in response to administration of endothelium-dependent vasodilator acetylcholine (dose range, 3 to 300 μg/min) into left main coronary arteries of 42 patients with chest pain and normal coronary angiographic findings and maximal increase in systolic wall thickening measured during dobutamine (40 μg/kg per min) stress echocardiography relative to baseline values. Maximal CBF response to acetylcholine was interpreted to represent maximal capacity of coronary microvascular endothelium to release relaxing factors. The 12 patients with ischemic-appearing ST segment depression during exercise (syndrome X) showed a pattern no different from that of the 32 patients with negative results of exercise treadmill tests (ETT). (Data from Cannon and associates.13)
Mayo Clinic Proceedings  , DOI: ( / )
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3. Fig. 2
Scatterplot showing absence of association between maximal increase in coronary blood flow (CBF) in response to infusion of endothelium-independent vasodilator adenosine (2.2 mg/min) into left main coronary arteries of patients assessed in Figure 1 and maximal increase in systolic wall thickening in response to administration of dobutamine. ETT = exercise treadmill test. (Data from Cannon and associates.13)
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions