1. Volume 13, Issue 1, Pages 199-207 (January 2016)
Safety of American Heart Association-recommended minimum exercise for desmosomal mutation carriers 
Abhishek C. Sawant, MD, MPH, Anneline S.J.M. te Riele, MD, Crystal Tichnell, MGC, Brittney Murray, MS, Aditya Bhonsale, MD, Harikrishna Tandri, MD, Daniel P. Judge, MD, Hugh Calkins, MD, FHRS, Cynthia A. James, ScM, PhD 
Heart Rhythm 
Volume 13, Issue 1, Pages (January 2016)
DOI: /j.hrthm
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2. Figure 1
Pedigrees of 10 families segregating a PKP2 mutation. Circles and squares represent women and men, respectively. Arrowhead represents the proband. Slanting bar indicates a deceased individual. Family members who were interviewed are indicated with an “I”. Filling of the circles/squares indicates diagnosis: white = unaffected, black = affected.
Heart Rhythm  , DOI: ( /j.hrthm )
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3. Figure 2
Cumulative lifetime MET-Hr exercise from two representative families (Family A and Family B). Accumulation of MET-Hr from age 10 is represented by a dotted line, which turns solid at diagnosis by 2010 Task Force Criteria and terminates at last follow-up. The shaded area represents MET-Hr that would accumulate based on consistently doing AHA-recommended minimum exercise (390–650 MET-Hr/year). Arrows represent first sustained ventricular arrhythmia. Probands (P) had done more exercise than their family members. MET-Hr = metabolic equivalent hour; TFC = 2010 Task Force Criteria; VT/VF = ventricular tachycardia/ventricular fibrillation (sustained ventricular arrhythmia).
Heart Rhythm  , DOI: ( /j.hrthm )
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4. Figure 3
Association of prior participation in endurance athletics with diagnosis by TFC (A) and VT/VF history (B). Family members who had been endurance athletes were significantly more likely to fulfill TFC and develop VT/VF. *Statistical significance P < .05. TFC = 2010 Task Force Criteria; VT/VF = ventricular tachycardia/ventricular fibrillation (sustained ventricular arrhythmia).
Heart Rhythm  , DOI: ( /j.hrthm )
Copyright © 2016 Heart Rhythm Society Terms and Conditions

5. Figure 4
Median exercise intensity (MET-Hr/year) before diagnosis in 5-year age increments compared to the AHA-recommended minimum stratified by diagnosis by TFC (A) and VT/VF history (B). Dotted black line represents the upper bound of the American Heart Association (AHA)-recommended minimum exercise (650 MET-Hr/year). Error bars depict interquartile range. *Statistically significant P < .05. MET-Hr = metabolic equivalent hours; TFC 2010 Task Force Criteria; VT/VF = ventricular tachycardia/ventricular fibrillation (sustained ventricular arrhythmia).
Heart Rhythm  , DOI: ( /j.hrthm )
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