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Counting Motors by Force

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Presentation on theme: "Counting Motors by Force"— Presentation transcript:

1 Counting Motors by Force
Daniel St Johnston  Cell  Volume 135, Issue 6, Pages (December 2008) DOI: /j.cell Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Stall Force Measurements Reveal the Number of Active Motors on Individual Lipid Droplets Lipid droplets undergo bidirectional movements along microtubules powered by kinesin-1 (blue) and dynein (orange) in the early Drosophila embryo (syncytium). Using a custom-built optical trap with an infrared laser (red), Shubeita et al. (2008) measured the forces required to stall the movement of lipid droplets along microtubules. This enabled them to count the number of active motors per droplet and to correlate this number with droplet dynamics. Cell  , DOI: ( /j.cell ) Copyright © 2008 Elsevier Inc. Terms and Conditions


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