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Joseph A. Odhiambo, MMed, Hywel C. Williams, PhD, Tadd O

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1 Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three 
Joseph A. Odhiambo, MMed, Hywel C. Williams, PhD, Tadd O. Clayton, MSc, Colin F. Robertson, MD, M. Innes Asher, MBChB  Journal of Allergy and Clinical Immunology  Volume 124, Issue 6, Pages e23 (December 2009) DOI: /j.jaci Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 World maps showing prevalence of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less than 5%, green circles indicate prevalence of 5% to less than 10%, yellow diamonds indicate prevalence of 10% to less than 15%, and red stars indicate prevalence of 15% or more. Europe is shown in greater detail in the inset section. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 2 Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Questions on eczema symptoms used in ISAAC Phase Three.
Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6 World maps showing prevalence of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less than 1%, green circles indicate prevalence of 1% to less than 1.5%, yellow diamonds indicate prevalence of 1.5% to less than 2%, and red stars indicate prevalence of 2% or more. Europe is shown in greater detail in the inset section. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7 Ranked prevalence plots of current symptoms of eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Regions are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

8 Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

9 Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

10 Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

11 Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

12 Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current symptoms of eczema (D), current symptoms of severe eczema (E), and lifetime reported “eczema” (F) for the age group 13 to 14 years. Each symbol represents a center. The line of equality is shown on each plot. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

13 Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current symptoms of eczema (D), current symptoms of severe eczema (E), and lifetime reported “eczema” (F) for the age group 13 to 14 years. Each symbol represents a center. The line of equality is shown on each plot. Journal of Allergy and Clinical Immunology  , e23DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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