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Figure 2 Mean serum concentrations of BIIB033 vs time(A) Single ascending dose study and (B) multiple ascending dose study. Mean serum concentrations of.

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Presentation on theme: "Figure 2 Mean serum concentrations of BIIB033 vs time(A) Single ascending dose study and (B) multiple ascending dose study. Mean serum concentrations of."— Presentation transcript:

1 Figure 2 Mean serum concentrations of BIIB033 vs time(A) Single ascending dose study and (B) multiple ascending dose study. Mean serum concentrations of BIIB033 vs time(A) Single ascending dose study and (B) multiple ascending dose study. EC50 and EC90 values determined in rat lysolecithin-induced demyelination spinal cord model; values adjusted for 0.1% brain penetration. Abbreviations: EC50 and EC90 = 50% and 90% maximal effective concentrations; SC = subcutaneous. Jonathan Q. Tran et al. Neurol Neuroimmunol Neuroinflamm 2014;1:e18 © 2014 American Academy of Neurology


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