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A Systematic Review and Meta-analysis of D-dimer as a Rule-out Test for Suspected Acute Aortic Dissection Stephen E. Asha, MBBS, MMed (Clin Epi), James W. Miers, BSc, MBBS Annals of Emergency Medicine Volume 66, Issue 4, Pages (October 2015) DOI: /j.annemergmed Copyright © 2015 American College of Emergency Physicians Terms and Conditions
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Figure 1 Flowchart describing systematic literature search and study selection process. Annals of Emergency Medicine , DOI: ( /j.annemergmed ) Copyright © 2015 American College of Emergency Physicians Terms and Conditions
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Figure 2 Individual study estimates and overall estimates of sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of D-dimer for the diagnosis of acute aortic dissection. A threshold of 0.50 μg/mL was used to define a positive D-dimer result. TP, True positive; FN, false negative; TN, true negative; FP, false positive; LR, likelihood ratio. *The discrepancy between the ratio and the reported positive likelihood ratio is because cells in 2×2 tables with zero value were handled by adding a 0.5 continuity correction. Annals of Emergency Medicine , DOI: ( /j.annemergmed ) Copyright © 2015 American College of Emergency Physicians Terms and Conditions
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Figure 3 Acute aortic dissection risk score.3,24
Annals of Emergency Medicine , DOI: ( /j.annemergmed ) Copyright © 2015 American College of Emergency Physicians Terms and Conditions
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