1. ARCHITECT c 16000 / c 8000 Differences
4/12/2019
ARCHITECT c / c Differences
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©2006, Abbott Laboratories,
Abbott Park, Illinois
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2. ARCHITECT c 16000 / c 8000 Differences
4/12/2019
ARCHITECT c / c 8000 Differences
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Revision or Release Date
Content or Pages Revised, Added, or Deleted
12/05/2006
New Release
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©2006, Abbott Laboratories,
Abbott Park, Illinois

3. 4/12/2019
Purpose
This presentation highlights the significant differences between the ARCHITECT c and c 8000 systems and should be used in conjunction with the ARCHITECT c Online Help.
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

4. Location of components Dual line feature Loading onboard solutions
Topics
Location of components
Dual line feature
Loading onboard solutions
Loading reagents
Assay Files
Maintenance Changes
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

5. Location of Components
4/12/2019
Location of Components
The location of the following c components has changed when compared to the c 8000 system.
Front: Rear:
- Sample and Reagent Syringes - ICT Aspiration Pump
- Probe Wash Pumps - ICT Reference Pump
- Bulk Solution Supply - High Concentration Waste Pump
- Wash Solution Pumps
- Cuvette Wash Pump
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©2006, Abbott Laboratories,
Abbott Park, Illinois

6. Location of Components (cont’d)
4/12/2019
Location of Components (cont’d)
ARCHITECT c supply and pump center components
Front View
(1) Sample, reagent 1 and reagent 2 syringe drives
(2) Probe wash pumps
(3) Bulk solutions
(4) Cuvette wash pump
(5) Wash solution pump
Rear View
(1) ICT aspiration pump
(2) ICT reference solution pump
(3) High concentration waste pump
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

7. Dual Line Feature
The c uses a dual line feature to pair assays for each run improving the throughput of the c
The system aspirates reagent for two assays, one assay on a designated “A-line” and the other assay on a designated “B-line”, in the same cycle.
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©2006, Abbott Laboratories,
Abbott Park, Illinois

8. Dual Line Feature (cont’d)
Both Reagent Supply Centers (R1 and R2) consist of an inner and outer carousel
Outer carousel = A-line (shaded)
Inner carousel = B-line (unshaded)
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©2006, Abbott Laboratories,
Abbott Park, Illinois

9. Dual Line Feature (cont’d)
4/12/2019
Dual Line Feature (cont’d)
The following components exist in pairs (A and B) to accommodate dual line technology :
Reagent probes, R1 & R2
Mixers, R1 & R2
Reagent syringes, R1 & R2
Cuvette washer nozzles 1-8 (total nozzles = 16)
Probe wash pumps
Wash solution pump (alkaline & acid)
NOTE: A single sample probe dispenses sample into two separate cuvettes (A and B) during a single cycle.
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

10. Loading onboard solutions
4/12/2019
Loading onboard solutions
Onboard solutions consist of Wash Solutions, ICT Diluent, Saline, and Water Bath Additive.
Differences in loading onboard solutions are displayed in the following table:
Onboard solution
c loading
c 8000 loading
Detergent A
10% Detergent B
0.5% Acid wash
R1 & R2 (C1 & D1)
R1 & R2 (C2 & D2)
R1 & R2 (C3 & D3)
R1 & R2 (D1, E1 or E2)
Water bath additive
R1, A1
R2, A1
ICT Sample Diluent
R1, outer carousel only (any position)
R1 (any position)
Saline (for sample dilution)
R1, outer and inner carousel (as configured on Reagent Status screen)
R1 (as configured on Reagent Status screen)
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©2006, Abbott Laboratories,
Abbott Park, Illinois

11. Loading onboard solutions (cont’d)
4/12/2019
Loading onboard solutions (cont’d)
c Supply Status screen
c 8000 Supply Status screen
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©2006, Abbott Laboratories,
Abbott Park, Illinois

12. Loading Reagents Reagent cartridge Reagent supply center placement
4/12/2019
Loading Reagents
Reagents
Both cartridges of a two reagent assay must be placed on the same
line (A or B). Refer to Iron and Alkaline Phosphatase examples in table below:
ICT sample diluent must be placed in the outer carousel (A-line) of the R1
reagent supply center.
Reagent cartridge
Reagent supply center placement
Iron R1 cartridge
Iron R1 - outer carousel (A-line)
Iron R2 cartridge
Iron R2 – outer carousel (A-line)
Alk phos R1 cartridge
Alk phos R1 – inner carousel (B-line)
Alk phos R2 cartridge
Alk phos R2 – inner carousel (B-line)
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©2006, Abbott Laboratories,
Abbott Park, Illinois

13. Loading Reagents (cont’d)
4/12/2019
Loading Reagents (cont’d)
c Reagent Status screen
c 8000 Reagent Status screen
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©2006, Abbott Laboratories,
Abbott Park, Illinois

14. Loading Reagents (cont’d)
4/12/2019
Loading Reagents (cont’d)
Replenishing reagents with an active calibration curve
To avoid recalibration when replacing an empty reagent cartridge, load the new cartridge on the same line as the reagent with the Active calibration status.
NOTE: If a reagent with an Active calibration status is moved from one line to the other (A/B) and scanned, the calibration status for that reagent changes to No Cal.
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

15. Assay Files Assay Import Message Description
4/12/2019
Assay Files
Assay Import
When you copy an assay file from an ARCHITECT c 8000 System to an ARCHITECT c System (or vice versa), the sample probe wash protocol and/or wavelength assay parameters may change. A status message displays to indicate this change during the import process.
Message
Description
OK - Multiple parameters converted,
review Message History.
The following assay parameters were changed:
• Sample wash protocol for sample probe changed from Optimized throughput (c 8000 only) to Maximum wash (c 8000 and c 16000). See Add / edit SmartWash window – Sample probe view (c System) field descriptions.
• Primary wavelength and/or Secondary wavelength. See Configure assay parameters window – General – Reaction definition view (photometric – c System) field Descriptions.
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

16. Assay Files (cont’d) Assay Import (cont’d) Message Description
OK - Sample wash protocol for sample probe converted to Maximum Wash
Sample wash protocol for sample probe changed
from Optimized throughput (c 8000 only) to Maximum
wash (c 8000 and c 16000). See Add / edit SmartWash
window – Sample probe view (c System) field
descriptions.
OK - One or more wavelengths were
changed.
Primary wavelength and/or Secondary wavelength.
See Configure assay parameters window – General –
Reaction definition view (photometric – c System) field
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

17. Assay Files (cont’d) c 16000 c 8000 Assay Wavelength Changes 416 412
The following wavelengths are different on the c16000 and c8000 systems:
c 16000
c 8000
416
412
450
444
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois

18. 4/12/2019
Maintenance Changes
The following daily and weekly maintenance procedures have been modified. These changes apply to both the c and c 8000 systems.
Current c 8000 procedure
New c system procedure
Daily Maintenance
Check 1mL Syringes
Procedure name did not change
Moved the following maintenance step to
Weekly maintenance:
- Check ICT aspiration and reference
pump 1 mL syringes.
Weekly Maintenance
6019 – Check ICT Probe and
Tubing
Procedure name changed to
6019 – Check ICT components.
Added the following maintenance step:
- Check ICT aspiration and reference
reference pump 1 mL syringes.
Document Control Number
©2006, Abbott Laboratories,
Abbott Park, Illinois