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New Perspectives for Your nAMD Patients

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Presentation on theme: "New Perspectives for Your nAMD Patients"— Presentation transcript:

1 New Perspectives for Your nAMD Patients

2

3 This program may include a discussion of data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.

4 Introduction

5 Undertreatment in Real-World Settings Can Lead to Suboptimal Gains in Vision

6 Real-World Evidence Shows That Over 70% of Patients With nAMD are Undertreated in the First Year of Therapy

7 Observational Study of FRB Database Eyes: Adherence to Treatment May Improve Results

8 The Number of Injections Affects VA Results

9 Objectives of the Treatments

10 Real-World Evidence Highlights the Relationship Between Injection Frequency and VA Gains

11 Sustain Treatment: Adequate and Continued Anti-VEGF Therapy Can Maintain Long-Term Vision in the Real World

12 Emerging Treatments for nAMD

13 Molecular Sizes of Anti-VEGF Agents

14 HAWK and HARRIER Studies: Brolucizumab Reduced Dosing Frequency

15 Patients treated with brolucizumab 6 mg had fewer visits in which  sub-RPE fluid was observed from Week 36 to 48

16 Conbercept for Choroidal Neovascularization Secondary to nAMD: The PHOENIX Study

17 Designed Ankyrin Repeat Protein (DARPin®): Abicipar Pegol

18 Phase 2 Studies Using RG7716

19 OPT-302 in PHASE 2B nAMD

20 HAWK and HARRIER Studies: Brolucizumab Reduced Dosing Frequency

21 HAWK and HARRIER: Study Design

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23 Phase 3 CEDAR and SEQUOIA

24 Conbercept for Choroidal Neovascularization Secondary to nAMD: The PHOENIX Study

25 Targeting Key Angiogenic Pathways With RG7716

26 RG7716 in the BOULEVARD Study

27 Phase 2 Studies Using RG7716

28 Phase 1/2a Data of OPT-302 in nAMD

29 Gene Therapy: The Example of RGX-314

30 Conclusions

31 Abbreviations


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