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Treatment options for HUS secondary to Escherichia coli O157:H7

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Presentation on theme: "Treatment options for HUS secondary to Escherichia coli O157:H7"— Presentation transcript:

1 Treatment options for HUS secondary to Escherichia coli O157:H7
Martin Bitzan  Kidney International  Volume 75, Pages S62-S66 (February 2009) DOI: /ki Copyright © 2009 International Society of Nephrology Terms and Conditions

2 Figure 1 Clinical spectrum and evolution of infections by Shiga toxin-producing Escherichia coli. Arrow thickness indicates the risk or likelihood of that particular outcome. Kidney International  , S62-S66DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions

3 Figure 2 Schematic diagram depicting the pathogenesis of Shiga toxin-producing Escherichia coli disease and putative interventions. LPS (lipopolysaccharide), Stx (Shiga toxin), STmAb (Stx-neutralizing monoclonal antibody), SAPK (stress-activated protein kinase [p38, JNK]). The numbers refer to therapeutic categories (see text). Kidney International  , S62-S66DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions


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