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Keeping your child healthy Pediatric Immunity By Elizabeth Large, ND Sept 2012 Gordon Medical Associates 707.575.5180

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Presentation on theme: "Keeping your child healthy Pediatric Immunity By Elizabeth Large, ND Sept 2012 Gordon Medical Associates 707.575.5180"— Presentation transcript:

1 Keeping your child healthy Pediatric Immunity By Elizabeth Large, ND Sept 2012 Gordon Medical Associates 707.575.5180

2 Stress/Trauma/Psychosocial stressors Nutrient poor diet, excess sugar. Chronic infection: parasites, fungal, bacterial, lyme or tick borne infection, chronic viral infections, mycoplasma p. Allergies, eczema, asthma Premature birth Lack of breast feeding Vaccination Environment: Lead exposure, mold toxicity, WIFI, air, water. Medication: Steroidal inhalers, antibiotics Food allergies or intolerances Genetics COMMON CAUSES OF IMMUNE DEFICIENCY

3 Frequent cold, flus, respiratory infection, sinusitis, tonsillitis. The child gets sick frequently. Illnesses linger and/or are more serious. True Immunodeficiency or Antibody deficiency = 8+ episodes of otitis media, 2+ serious sinus infections, or 2+ episodes of pneumonia in 1 year. Allergies, eczema, asthma. Lyme or Tick Borne Disease, Chronic viruses. IMPAIRED IMMUNITY

4 USA: Birth to 6 years – 44 vaccinations including influenza once a year 32 European countries: Birth to 16 years: 22 vaccinations WHAT IS SAFE VACCINATION? Check titers to confirm immunity for MMR Avoid all vaccines with thimersol Never vaccinate an ill child VACCINATION 2012

5 Request only single dose vaccines No Hep B until 2 years old Do not give vaccine if child allergic to one of the components: Yeast- Hep B, Eggs –MMR, Neomycin – MMR or Varicella Read: The Vaccine Guide: Making an Informed Choice, by Randall Neustaedter, M.D. Give MMR at 15 mo, Mumps-21, Rubella-27mo SAFE VACCINATION

6 Human breast milk contains large quantities of secretory Ig A (sIgA). These antibodies, can bind to potential pathogens and prevent their attachment to the infant's cells. Colostrum: Present first 2 weeks,, contains levels of white blood cells. Most of these white blood cells are macrophages and neutrophils, which phagocytose microbial pathogens. The bodies natural vaccine against viruses and bacteria. BREAST FEEDING

7 Toxicity linked to a growing amount of chronic disease and developmental abnormalities. Sources: toys, breast milk, mother during pregnancy, environment, medications, water, food, vaccinations, plastics used for toys and food. Results of toxic overload: Immune dysregulation Immune activated hyper-coagulability Chronic dysbiosis Impaired detoxification Increased Sensitivity Genetic polymorphisms TOXICITY

8 70-80% of your immunity. Good place to begin treatment. Health enhancing intestinal bacteria serve to prevent the overgrowth of potentially harmful bacteria in the gut. Estimated 80-85% beneficial bacteria and 15- 20% pathogenic bacteria is normal ratio. Harmful microorganisms are kept in check by the GALT. Intestines contain the largest mass of lymphoid tissue in the body. This tissue stores immune cells that defend against pathogens. GI IMMUNITY

9 Cause: balance of flora in the intestine is tipped towards having more bad bacteria and yeasts than good. Causes: Over use of antibiotics at an early age Inherited from mother Use of steroidal medication Overconsumption of sugar and simple carb foods such as cake, cookies, crackers, cereal. DYSBIOSIS

10 Dysbiosis lowers immunity by reducing sigA, creating susceptibility to acute infections. Overgrowth of pathogenic bacteria, different strains of candida and possibly parasites. Treatment: Must involve anti-fungals/antibacterials, sugar free or yeast free diet and replenishing good bacteria, healthy diet with low sugar. Yeast: Nystatin, diflucan, grapefruit seed extract Bacteria: Capryllic acid, garlic, GSE, olive leaf, etc. Probiotics: Acidophilus, Bifidobacteria. Immune modulation homeopathics DYSBIOSIS

11 A Healthy Gut: Allows properly digested food to pass into the bloodstream to be used for fuel. Acts as a barrier to keep out foreign invaders such as bacteria, viruses, and undigested food particles. An Unhealthy Gut: The protective barrier is broken down, poorly digested food particles and bacteria can flood the system. Act as antigens triggering the immune system. LEAKY GUT SYNDROME

12 Symptoms include: Stuffed nose, runny nose, sinus problems Hypoglycemia, mood swings, tantrums Nervousness, palpitations, memory or concentration problems, fuzzy thinking, malaise Abdominal pain, constipation, diarrhea, bloating, gas, indigestion, digestive problems Allergies, asthma, eczema, headaches, low immunity, autoimmune, rashes, itchiness LEAKY GUT SYNDROME

13 Chronic recalcitrant infections, think biofilm especially in sinuses. Biofilms are natures adaptive mechanisms to wall off protecting the organisms within. May prevent Antibiotics or immune herbs from reaching the desired destination (bacteria). Examples: chronic ear infections, chronic sinusitis, lyme, polymyxoa rheumatica. Breaking down biofilms requires using specific enzymes with EDTA plus antibiotic or antibacterial herbs, Samento, Mucor. CHRONIC INFECTION

14 Immune regulation can occur due to an imbalance in TH!/TH2. Overactivation of either pattern can cause disease, and either pathway can down-regulate the other. Th1 – Drives cellular immunity or defense against intracellular organisms such as viruses, intracellular pathogens, and cancer cells. Th1 upregulated illness = RA, Lyme, Crohns, MS, IDDM. TH2 – Drives humoral immunity which defends against extracellular organisms. Responsible for production of antibodies. TH2 dominant illness: Allergic disorders, asthma, eczema, scleroderma, SLE. TH1/TH2 IMBALANCE

15 Methylation is a complex mechanism involved in many important functions in the body. Methylation errors acquired or genetically determined. Important for normal immune function. The methylation cycle is essential for cell mediated immune function and blockages here will mean that infections will not be adequately dealt with. Synthesis of glutathione which is essential for detoxification. Turns on and off DNA. This is essential for gene expression and protein synthesis. Proteins of course make up the hormones, neurotransmitters, enzymes, immune factors. When viruses attack our bodies, they take over our own DNA in order to replicate themselves. If we can't switch DNA/RNA replication off then we will become more susceptible to viral infection. METHYLATION ERRORS

16 Often those who have chronic immunodeficiency have underlying genetic methylation defects (polymorphism). If the methylation cycle doesnt work than the immune system doesnt work. Tests: Genetic methylation panel -Amy Yasko - Methylation levels -Health Vitamin Diagnostics Plasma Homocysteine, high or low. Methylation requires using nutrients to bypass the genetic defects: METHYLATION Methyl/hydroxy B12 5-methyltetrahydrofolate Folinic acid B6 or P5P Phosphatidylserine Phosphatidylcholine TMG DMG SAMe Methionine Glutathione.

17 Vitamin A deficiency is found in kids who live on meat, potatoes and junk. Antioxidant that protects against infections. Acute and Chronic viruses deplete stores. Sources: animal liver, animal and diary fat from pastured animals. 2500-5000 IU per day from Cod liver oil. Fat soluble vitamin. Zinc is needed for cellular and humoral immunity. Zinc rich foods are: roast beef, roasted pumpkin and squash seeds, dark chocolate and cocoa powder, lamb, peanuts, crab. Supplementation is 5-30 mg per day. Vitamin D increases immunity and decreases autoimmunity. Sunlight, animal fat (those raised on pasture with access to sunlight) such as butter and diary. 1000-5000 iu per day. Reduces respiratory infections, flu. VITAMIN DEFICIENCY

18 Magnesium – Useful in allergic disorders, constipation, chronic stress, irritability, insomnia or muscle cramps, colic, behavioral problems. Nuts, seeds, almonds, oats, buckwheat, beans, green vegies. Iron – Too much milk consumption blocks absorption of iron. Raisins, meats (especially liver), fish, poultry, egg yolks, legumes (peas and beans), and whole-grain bread. Assoc. with gluten intolerance. Sx: fatigue, pica, dizziness. VITAMIN DEFICIENCY

19 Omega-3 fatty acids reduce TH2 cytokines Studies have shown that people who have allergies need more EFAs than people who dont. Enzyme defect in conversion from LA to GLA. This might explain family susceptibility. Signs and Symptoms: Behavior and learning problems, eczema, asthma, thirst and allergies EFA DEFICIENCY

20 Studies have shown that drinking the equivalent of two and a half 12-ounce cans of soda can reduce white blood cells by 40%. The average person eats 33 Tablespoons of sugar daily. May destabilize blood sugar levels and later lead to adrenal insufficiency. Feeds yeast and pathogenic bacteria in the gut. SUGAR

21 IgG allergy: Worst offending foods – dairy, gluten, eggs, wheat, corn. Food intolerance or sensitivities are much more common than true allergy. Caffeine, chocolate, sugar, yeast, etc. Often produce delayed reactions Best test: Elimination Diet for 3-4 weeks Underlying problem may be Dysbiosis/Leaky Gut and yeast overgrowth. FOOD ALLERGY/INTOLERANCE

22 There is no safe threshold for toxins. In 1960, it was believed that 60 mcg/dl was a safe level of lead. In 1991 it was 10 mcg/dl. Pesticides/herbicides, toxic chemicals, bisphenol A, pthalates, heavy metals, PCBs, DDT, etc. Glutathione (the bodies important antioxidant, detoxifier and immune booster to the NK cells (front line of immune defense) Increased toxins = Decreased immunity ENVIRONMENT

23 Mold exposure is common and is considered a biotoxin which triggers an immune response. Common symptoms: Chronic cough, fatigue, suppressed immunity, recurrent bronchitis, sinusitus, headaches, nose bleeds, asthma, swollen glands, memory loss, mold and dust sensitivity and many more. If you suspect mold: ERMI test from MOLD EXPOSURE

24 Lead-based paints were banned for use in housing in 1978. All houses built before 1978 are likely to contain some lead-based paint. However, it is the deterioration of this paint that causes a problem. Other sources: soil, water, lead glazed ceramics, air from industrial sources, cosmetics, herbs/foods from china, lead solder in pipes. Childhood exposure causes reduced intelligent quotient (IQ), learning disabilities, attention deficit disorders, behavioral problems, stunted growth, hearing problems, anemia, kidney damage and stomach pain. LEAD

25 Chronic stressors are associated with suppression of both cellular and humoral immunity. Ongoing stress, anxiety and/or poor sleep also stresses the adrenal glands. Long term high cortisol production will create adrenal insufficiency lowering the threshold for stress and compromising immunity. CHRONIC STRESS

26 Organic and pasture fed meats. Non-gmo as much as possible. (GMO-soy, canola oil, sugar beets, corn) Variety of organic vegetables/fruits. Minimal sugar intake. Minimal to no juice or sugar drinks. Whole foods – whole grain vs. processed. Good fats- olive oil, coconut oil, organic butter IMMUNE SUPPORT BEGINS WITH DIET

27 A specific diet may needed to deal with the childs particular problem. Gluten and/or Casein Free Specific Carbohydrate Diet Candida Diet Elimination Diet Gut and Psychology Diet (GAPS Diet) Body Ecology Diet SPECIAL DIETS

28 Those highest in vitamin C and antioxidants: Highest ORAC foods: Blueberries, blackberries, garlic, kale, strawberries, spinach. Yellow-orange fruits and dark green vegetables contain carotenoids - a natural substance that increases the production of infection-fighting white blood cells. : Tomatoes, broccoli, sweet potatoes and, such as apricots, carrots, pumpkin, kale, spinach, squash and mango, cantaloupe, papaya, guava. PROTECTIVE FRUITS/VEGIES

29 Supports immunity and decreases autoimmunity and inflammation. Richest source is raw nuts, seeds and fish. (salmon, mackeral, sardines, herring). One capsule fish oil or 2-3 teaspoons of flax oil a day. Cod Liver oil contains Vitamins A and D which support immunity. 1 tsp young children, 1T – adolescents. OMEGA 3 FATS

30 Powerful antoxidant, increases glutathione and immune function. Up to bowel tolerance is safe. 1000 mg per day is adequate unless acute illness, then 4-8000 mg per day. In one double-blind study, the average red blood cell glutathione concentration rose nearly 50% with 500 mg/day of vitamin C. Increasing the dosage to 2,000 mg only raised red blood cell (RBC) glutathione levels by another 5%. VITAMIN C

31 Vit. C 500-1000 mg 3-5 x per day or to bowel tolerance. Vit. A 10,000 iu per day up to 2 weeks. Children over 10 can take 100,000 iu per day. Over 120 lbs can take 200,00 per day for 3-5 days. Zinc lozenges up to 30 mg day. If given antibiotics, have doctor prescribe Nystatin to prevent yeast overgrowth. VITAMINS FOR ACUTE ILLNESS

32 Theory of Homotoxicology Health of extracellular matrix (ECM) is critical for the ability of nutrients to reach the cell and toxins to drain out. Intracellular communication also depends on the ECM. Inflammation and physical dysregulation results from a burdened ECM Homeopathic drainage medicine detoxifies the ECM. Excretion routes are liver, kidneys, skin, lymphatics. Examples of drainage remedies include: Bioresource, Energetix, Heel, Unda DETOXIFICATION

33 Exercise: Increases the white blood cells ability to fight off infection Improves circulation Increases natural endorphins Sweating releases toxins Reduces stress Improves attitude and well being. EXERCISE

34 Antivirals: Andrographis, Isatis herbs Homeopathics: Gelsemium, antimonium tartaricum, eupatorium, pulsatilla, chamomilla, spongia tosta Bioresource: Apo-tuss, Bronchi-pertu, Syinfect, Syimmune, Notatum, Quentans, Itires, Sydetox, etc. Vitamin C Herbal formulas for respiratory infections Chinese herbal formulas: Gan mao ling, yin chao Usually I give at least 1 herb, 1 homeopathic, and Vitamin C every 3 hours. ACUTE ILLNESS-FAVORITES

35 Vitamin B12: Immune modulator. Increases NK cells. Methyl B12 injections most effective for asthma and autism. Sublingual methyl B12 1000 mcg per day. Vitamin E: Spares glutathione and protects immune system from damage due to viral infections. Use Soy free form. 100-400 iu in mixed tocopherals. Vitamin C, Multi-vitamin, Probiotics, O-3 fish oil Astragalus, elderberry Medicinal mushrooms Immunomodulators Transfer Factor, IgG 2000, Colostrum to increase sigA. PREVENTATIVE IMMUNE SUPPORT

36 Nourishing Hope for Autism, Julie Matthews Healing the New Childhood Epidemics: Autism, ADHD, asthma, and Allergies: The Ground breaking Program for the 4A disorders, Kenneth Bock A Compromised Generation: The Epidemic of Chronic Illnesses in Americas Children, Beth Lambert and Victoria Kobliner RECOMMENDED READING

37 Superimmunity, by Leo Galland Homeopathic Medicine for Children and Infants, Dana Ullman Is This Your Child? Discovering and Treating Unrecognized allergies in Children and Adults by Doris Rapp What Your Doctor May Not Tell You About Vaccinations by Stephanie Cave, MD Movie on GMO – Genetic Roulette RECOMMENDED READING


39 Elizabeth Large ND Gordon Medical associates Unravelling Complex Chronic Illness 3471 Regional Parkway Santa Rosa, CA 95403 707.575.5180 CONTACT

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