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Presentation on theme: "Copyright Notice This presentation is copyrighted by the Psychopharmacology Institute. Subscribers can download it and use it for professional use. The."— Presentation transcript:

1 Copyright Notice This presentation is copyrighted by the Psychopharmacology Institute. Subscribers can download it and use it for professional use. The contents of the presentation may be modified, but the Psychopharmacology Institute logo must remain visible in all slides.

2 A Treatment Algorithm for TRD
Prof. Philip Cowen Professor of Psychopharmacology Department of Psychiatry University of Oxford, UK

3 Treatment algorithm for TRD

4 Treatment algorithm for TRD
Every patient requires an individual assessment Treatment history Symptoms Extent of their disability

5 Treatment algorithm for TRD
Every patient requires an individual assessment Treatment history Symptoms Extent of their disability

6 Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

7 First line: Escitalopram Venlafaxine
Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

8 First line: Escitalopram: 20 mg/day
Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

9 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

10 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

11 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

12 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Lithium Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

13 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Lithium TCAs Amitriptyline Clomipramine Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

14 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Lithium TCAs Amitriptyline Clomipramine MAOI Tryptophan Phenelzine Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

15 Venlafaxine: up to 375 mg/day
First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Lithium TCAs Amitriptyline Clomipramine MAOI Tryptophan Phenelzine ECT Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

16 Venlafaxine: up to 375 mg/day
MAOI Phenelzine TCAs Amitriptyline Clomipramine First line: Escitalopram: 20 mg/day Venlafaxine: up to 375 mg/day Atypical antipsychotics Mirtazapine Lithium Psychotherapy CBT MBCBT Tryptophan ECT Cowen PJ, Anderson IM (2015). New approaches to treating resistant depression. BJPsych Advances 21,

17 End of presentations


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