1. You need: Clean paper / pencil Warm Up: Mental Math I CAN: demonstrate the phases (and functions of each phase) of mitosis.
Mar. 2, 2018

2. MITOSIS

3. Starting point:
You want to start with one cell that has 100% of the genetic information (like a normal body cell). To keep things simple, we will work with a cell that has 4 chromosomes in a normal body cell.

4. Your goal:
To create TWO cells that each have 100% of the genetic information. These would have FOUR chromosomes each…and look just like the original.

5. START
Anaphase
Interphase
Prophase
Telophase
Metaphase
Cytokinesis

6. Did you reach the goal? Two cells and each has exactly 100% of the genetic material? Is the genetic material the same in these cells? Is that good or bad? Why?

7. Mitosis – from the Amoeba sisters
Watch this YouTube video from a group that call themselves the Amoeba sisters!

8. Animal Mitosis -- Review
Interphase                                                             
Prophase                                                             
Metaphase                                                             
Anaphase                                                             
Telophase                                                             

9. Plant Mitosis -- Review
Interphase                                                             
Prophase                                                             
Metaphase                                                             
Anaphase                                                             
Telophase                                                             

10. Interphase Description of events: Centriole pair replicates.
DNA replicates to create duplicated chromosomes.
Most of the cell’s life is spent in INTERPHASE

11. Prophase Description of events:
Centriole pair begins to migrate to opposite poles.
Nuclear membrane begins to dissolve.
Spindle fibers begin to form between centriole pairs.
Duplicated chromosomes begin to condense.
Nucleolus begins to disappear.

12. Metaphase Description of events:
Centriole pairs are fully migrated to opposite poles.
The spindle apparatus is fully formed.
Spindle fibers have moved the duplicated chromosomes so that they line up at the midline of the cell.
Nuclear membrane has completely disappeared.
Duplicated chromosomes are at their most condensed at this stage.

13. Anaphase Description of events:
Spindle fibers pull the sister chromatids apart at the centromere and drag them to opposite poles.
The cell elongates (gets longer – like an oval)

14. Telophase Description of events:
The cell begins cytokinesis by forming a cleavage furrow (pinch) to divide the cytoplasm.
Nuclear membranes begin to reform around the separate (but identical) sets of chromosomes.
Spindle apparatus has disassembled and the spindle fibers dissolve.
Chromosomes begin to de-condense.
Nucleolus begins to re-form.
Telophase

15. After cytokinesis Description of events:
The two identical daughter cells are completely separated.
Spindle fibers have completely disappeared.
The chromosomes are completely de-condensed and lengthened.
The nucleolus is very distinct.
The nuclear membrane has completely re-formed around the chromosomes.
After cytokinesis

16. Check over your work!!

17. Interphase Anaphase Prophase Telophase Metaphase After cytokinesis
Description of events:
Centriole pair replicates.
DNA replicates to create duplicated chromosomes.
Most of the cell’s life is spent in INTERPHASE
Description of events:
Spindle fibers pull the sister chromatids apart at the centromere and drag them to opposite poles.
The cell elongates (gets longer – like an oval)
Anaphase
Prophase
Description of events:
Centriole pair begins to migrate to opposite poles.
Nuclear membrane begins to dissolve.
Spindle fibers begin to form between centriole pairs.
Duplicated chromosomes begin to condense.
Nucleolus begins to disappear.
Description of events:
The cell begins cytokinesis by forming a cleavage furrow (pinch) to divide the cytoplasm.
Nuclear membranes begin to reform around the separate (but identical) sets of chromosomes.
Spindle apparatus has disassembled and the spindle fibers dissolve.
Chromosomes begin to de-condense.
Nucleolus begins to re-form.
Telophase
Metaphase
Description of events:
Centriole pairs are fully migrated to opposite poles.
The spindle apparatus is fully formed.
Spindle fibers have moved the duplicated chromosomes so that they line up at the midline of the cell.
Nuclear membrane has completely disappeared.
Duplicated chromosomes are at their most condensed at this stage.
Description of events:
The two identical daughter cells are completely separated.
Spindle fibers have completely disappeared.
The chromosomes are completely de-condensed and lengthened.
The nucleolus is very distinct.
The nuclear membrane has completely re-formed around the chromosomes.
After cytokinesis

19. Mitosis Hand Jive!
Here are two videos that explain the hand motions used to represent phases of mitosis. Watch them both!!!
Bill Ry the science guy EXPLAINS the hand signals.
Ms. Loree dances through the mitosis hand signals.

20. Mnemonic Device
Sometimes it helps us to remember things if we put it into a song, or hand signals, or a crazy sentence.
You may have used “Please Excuse My Dear Aunt Sally.” The first letter of each word matches the steps in the order of operations (parentheses, exponents, multiply/divide, add/subtract).
Come up with a Mnemonic Device using the letters of the phases of mitosis (IPMATC). Turn it in through Google Classroom

21. IPMATC REMEMBER! Interphase Prophase Metaphase Anaphase Telophase
Cytokinesis
IPMATC
A mnemonic to help remember the stages of mitosis.
Iguanas Pee More Accurately Than Cats.