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A systematic review and meta-analysis of abdominal compartment syndrome after endovascular repair of ruptured abdominal aortic aneurysms  Christos D.

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Presentation on theme: "A systematic review and meta-analysis of abdominal compartment syndrome after endovascular repair of ruptured abdominal aortic aneurysms  Christos D."— Presentation transcript:

1 A systematic review and meta-analysis of abdominal compartment syndrome after endovascular repair of ruptured abdominal aortic aneurysms  Christos D. Karkos, MD, FRCS, PhD, EBIR, Georgios C. Menexes, BMath, MA, PhD, Nikolaos Patelis, MD, Thomas E. Kalogirou, MD, MSc, Ioakeim T. Giagtzidis, MD, Denis W. Harkin, MD, FRCS, FEBVS  Journal of Vascular Surgery  Volume 59, Issue 3, Pages (March 2014) DOI: /j.jvs Copyright © 2014 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Forest plot shows the random effects proportion meta-analysis for abdominal compartment syndrome (ACS) rates after endovascular repair in the 39 studies with available information. The first number at the end of the line for each study represents the proportion, with the two numbers in parenthesis indicating the 95% confidence interval (CI). The solid black squares denote the ACS rate for each study and the horizontal lines represent the 95% CIs. The pooled estimate is marked with an unfilled diamond that has an ascending dotted line from its upper point, and the 95% CI is displayed as a horizontal line through the diamond. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Forest plot shows the random effects proportion meta-analysis for abdominal compartment syndrome (ACS) rates after endovascular ruptured abdominal aortic aneurysm (RAAA) repair (A) in the six studies that provided an accurate definition of ACS and (B) in the four studies that focused specifically on the development of ACS after endovascular repair of RAAAs. The first number at the end of the line for each study represents the proportion, with the two numbers in parenthesis indicating the 95% confidence interval (CI). The solid black squares denote the ACS rate for each study and the horizontal lines represent the 95% CIs. The pooled estimate is marked with an unfilled diamond that has an ascending dotted line from its upper point, and the 95% CI is displayed as a horizontal line through the diamond. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Weighted scatter plot between hemodynamic instability and mortality shows a moderate positive linear correlation (r = 0.303). This correlation is more obvious for proportions of unstable patients between 0.30 and 0.45, as noted by the Loess curve (dotted red line). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Nonlinear meta-regression plots between the bifurcated endograft approach and mortality are shown for (A) the second-degree model with 95% confidence belts and (B) by the Loess curve (dotted red line). The model suggest that mortality shows an increasing trend for centers performing low percentages of bifurcated endografts (<50%) and a decreasing trend for centers performing high percentages of bifurcated endografts (>50%). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

6 Fig 5 Algorithm for escalation of management of abdominal compartment syndrome (ACS) after endovascular repair of ruptured abdominal aortic aneurysms (RAAAs). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions


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