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Patrick T. O'Gara, MD, MACC, FAHA, Thoralf M. Sundt, MD, Michael A

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Presentation on theme: "Patrick T. O'Gara, MD, MACC, FAHA, Thoralf M. Sundt, MD, Michael A"— Presentation transcript:

1 The Cardiothoracic Surgical Trials Network: Implications for clinical practice 
Patrick T. O'Gara, MD, MACC, FAHA, Thoralf M. Sundt, MD, Michael A. Acker, MD, Tirone E. David, MD, Robert E. Michler, MD, Michael A. Borger, MD, Gorav Ailawadi, MD, Vinod H. Thourani, MD, A. Marc Gillinov, MD, Ralph J. Damiano, MD, Michael J. Mack, MD, Richard Lee, MD, Eric A. Rose, MD, Timothy J. Gardner, MD, Marissa A. Miller, DVM, MPH, Richard D. Weisel, MD, Annetine C. Gelijns, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 154, Issue 6, Pages (December 2017) DOI: /j.jtcvs Copyright © Terms and Conditions

2 Figure 1 Cumulative failure of mitral valve repair or replacement at 2 years. Failure of the intervention was defined as death, moderate or severe MR as seen on transthoracic echocardiography, or mitral reintervention. MR, Mitral regurgitation. From Goldstein and colleagues.16 Copyright © 2016 Massachusetts Medical Society. Reprinted with permission. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

3 Figure 2 Persistent more than moderate MR was greater after CABG alone than after CABG and MV repair. Presented at the American College of Cardiology Featured Clinical Research, April 3, MR, Mitral regurgitation; CABG, coronary artery bypass grafting; MV, mitral valve. From Michler and colleagues.17 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

4 Figure 3 Freedom from atrial fibrillation after MVS. Freedom from atrial fibrillation was defined as the absence of the condition at both 6 months and 12 months, as assessed by means of 3-day Holter monitoring. A, Freedom from atrial fibrillation after MVS for all patients with 6- and 12-month Holter data. B, Freedom from atrial fibrillation after MVS for the 106 patients in the MVS + ablation arm. CI, Confidence interval; MVS, mitral valve surgery; PVI, pulmonary vein isolation. From Gillinov and colleagues.24 Copyright © 2015 Massachusetts Medical Society. Reprinted with permission. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

5 Figure 4 Patients with no atrial fibrillation at 7 days. The figure shows the proportion of patients undergoing cardiac surgery who had a stable heart rhythm without atrial fibrillation during the first week after randomization in the rate-control group and the rhythm-control group. From Gillinov and colleagues.26 Copyright © 2016 Massachusetts Medical Society. Reprinted with permission. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

6 Cumulative failure of mitral valve repair or replacement at 2 years.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

7 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

8 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

9 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

10 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

11 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

12 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

13 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

14 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

15 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

16 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

17 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

18 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

19 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

20 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

21 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

22 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

23 The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions


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