1. Studies on Epidermis Reconstructed with and without Melanocytes: Melanocytes Prevent Sunburn Cell Formation but not Appearance of DNA Damaged Cells in Fair- Skinned Caucasians 
Muriel Cario-André, Catherine Pain, Alain Taïeb 
Journal of Investigative Dermatology 
Volume 115, Issue 2, Pages (August 2000)
DOI: /j x
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Spectral distribution of radiation emitted by the UVB fluorescent sunlamp used in this study.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Melanocytes protect against SBC formation. cf. Figure 4(b). Twenty-four hours following UVB irradiation, melanocytes remain mostly localized close to the basal layer and the rare sunburn cells (arrow) are localized mainly in the spinous layer. Immunohistochemistry localization of melanocytes by S100 antibodies and SBC by hematoxylin–eosin in REM following UVB irradiation (0.15J per cm2). Scale bar: 25 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

4. Figure 3
Melanosomes are melanized and transferred to keratinocytes. Melanosomes (arrows) observed by electron microscopy in keratinocytes of REM: (a) before irradiation and (b) 24h following UVB irradiation (0.15J per cm2). Scale bar: 1 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

5. Figure 4
Cellular hyperplasia, sunburn cell formation and granular cell death in reconstructs without melanocytes, 24h following UVB irradiation. (a) No SBC formation and no hyperplasia in nonirradiated REK. (b) Histologic evidence of granular cell death, SBC clusters (arrows) and epidermal cellular hyperplasia in REK 24h following UVB (0.10J per cm2). Scale bar: 50 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

6. Figure 5
The presence of melanocytes in reconstructs prevents epidermal cell death. Curves represent the time course appearance of eosinophilic cells (apoptotic and necrotic cells) after UVB irradiation (1.0 and 0.15J per cm2) in REK and REM. The asterisk indicates significant (p<0.05 t test) differences between irradiated REK or REM compared their nonirradiated controls.
Journal of Investigative Dermatology  , DOI: ( /j x)
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7. Figure 6
The presence of melanocytes does not change the number and the distribution of CPD-positive cells in reconstructs. CPD-positive cells 2h following UVB (0.10J per cm2) in (a) REM and (b) REK. Scale bar: 25 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
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8. Figure 7
The presence of melanocytes in reconstructs does not modify 6–4 PP production. Kinetics of appearance of 6–4 PP positive cells in REK and REM after UVB irradiation. (a) 0.10 J cm-2; (b) 0.15 J cm-2. The asterisk indicates significant (p<0.05) difference from control samples (unirradiated REM or REK).
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions

9. Figure 8
The presence of melanocytes in reconstructs does not modify CPD formation. Kinetics of appearance of CPD-positive cells in REK and REM after UVB irradiation. (a) 0.15 J cm-2; (b) 0.10 J cm-2. The asterisk indicates significant (p<0.05) difference from control samples (unirradiated REM or REK).
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2000 The Society for Investigative Dermatology, Inc Terms and Conditions