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Detection of Human Papillomavirus DNA in Cutaneous Squamous Cell Carcinoma among Immunocompetent Individuals  Maryam M. Asgari, Nancy B. Kiviat, Cathy.

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Presentation on theme: "Detection of Human Papillomavirus DNA in Cutaneous Squamous Cell Carcinoma among Immunocompetent Individuals  Maryam M. Asgari, Nancy B. Kiviat, Cathy."— Presentation transcript:

1 Detection of Human Papillomavirus DNA in Cutaneous Squamous Cell Carcinoma among Immunocompetent Individuals  Maryam M. Asgari, Nancy B. Kiviat, Cathy W. Critchlow, Joshua E. Stern, Zsolt B. Argenyi, Gregory J. Raugi, Daniel Berg, Peter B. Odland, Stephen E. Hawes, Ethel-Michele de Villiers  Journal of Investigative Dermatology  Volume 128, Issue 6, Pages (July 2008) DOI: /sj.jid Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Phylogenetic tree containing genus α-, β-, and γ-papillomaviruses. The outer circle encompasses genera, the inner circle the species, and the numbers at the ends of the branches identify type. C-numbers refer to candidate HPV types. The four numbers associated with the arrows show the total number of HPV-positive DNA samples detected in lesion, perilesion, sun-exposed and sun-protected tissues, respectively. (These numbers take into account multiple infections with the same species in a given subject and, therefore, may differ from those listed in Table 2.) (Figure is modified from a previously published version by De Villiers et al. (2004), with copyright permission granted by Elsevier.) Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 SCC of the ear demonstrating lesional and perilesional tissue. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions


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