1. Lectures this week: Cardiovascular
15 November 2010
Lectures this week: Cardiovascular
Lab this week: EKG, blood pressure, and heart sounds.
Wear clothes and shoes that will allow you to run during a portion of lab to look at the effects of exercise on heart rate and EKG waveforms.
Read about
EKGs on p of text.
Measuring blood pressure on p. 387

2. 1QQ # 28 for 8:30 1. Capillaries have
The slowest blood flow velocity of any vessel type
The smallest diameter of any blood vessel type
the highest resistance of any vessel type on an individual basis
Pulsatile blood flow
Smooth muscles and endothelial cells.
The aorta and the largest arteries have
Low compliance
Low resistance
Low pressure
Rigid, inelastic walls

3. 1QQ # 28 for 9:30 1. Capillaries have
The slowest blood flow velocity of any vessel type
The smallest diameter of any blood vessel type
the highest cumulative cross sectional area when all are considered together
Pulsatile blood flow
Smooth muscles and endothelial cells.
The aorta and the largest arteries have
High compliance
Low resistance
High pressure
Elastic walls

4. Cardiovascular responses to Exercise: A Real World Example
Actions of Hormones (Cortisol, EPI, Glucagon, Insulin) and effects on cardiac muscle, cardiac conduction system, arteriolar smooth muscle, adipose tissue…)
Q to GI tract, skeletal muscles, brain
Effects on HR, SV, EDV, CO, TPR, MAP
Intrinsic and extrinsic control of blood flow to capillaries
Absorptive and post-aborptive phase; uses of fuels during exercise.

5. Fig. 12.36 S 12 No parasympathetic innervation of arterioles!
Metabolic vasodilators
No parasympathetic innervation of arterioles!
Importance of sympathetic “tone.”
12.36.jpg
Metabolic autoregulation, flow autoregulation, myogenic autoregulation

6. Figure 12.02 Arteries = 10% of Blood Volume
Veins = 60% of Blood Volume
Arterioles = Resistance vessels
Capillaries = 5% of Blood Volume

7. S 14
Capillaries: Continuous, discontinuous, and fenestrated capillaries:
Ex: brain and liver
Figure 12.38
Generate vasodilators and vasoconstrictors
Arterioles:
1) Extrinsic control by hormones and nerves 2) Intrinsic (local) control by …..a) metabolic autoregulation, …..b) flow autoregulation, and …..c) myogenic autoregulation.

8. Diffusion, mediated transport, bulk flow