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A Dose Escalation Clinical Trial of Single-Fraction Carbon Ion Radiotherapy for Peripheral Stage I Non–Small Cell Lung Cancer  Naoyoshi Yamamoto, MD,

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Presentation on theme: "A Dose Escalation Clinical Trial of Single-Fraction Carbon Ion Radiotherapy for Peripheral Stage I Non–Small Cell Lung Cancer  Naoyoshi Yamamoto, MD,"— Presentation transcript:

1 A Dose Escalation Clinical Trial of Single-Fraction Carbon Ion Radiotherapy for Peripheral Stage I Non–Small Cell Lung Cancer  Naoyoshi Yamamoto, MD, PhD, Tadaaki Miyamoto, MD, PhD, Mio Nakajima, MD, PhD, Masataka Karube, MD, Kazuhiko Hayashi, MD, PhD, Hiroshi Tsuji, MD, PhD, Hirohiko Tsujii, MD, PhD, Tadashi Kamada, MD, PhD, Takehiko Fujisawa, MD, PhD  Journal of Thoracic Oncology  Volume 12, Issue 4, Pages (April 2017) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Outcomes after single-fraction carbon ion radiotherapy (CIRT) for local control (LC) in patients receiving 36.0 to 50.0 Gy (relative biological effectiveness [RBE]) versus 28.0 to 34.0 Gy (RBE). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 (A) Overall survival (OS) in patients receiving 36.0 to 50.0 Gy (relative biological effectiveness [RBE]) versus 28.0 to 34.0 Gy (RBE). (B) Progression-free survival (PFS). Abbreviation: CIRT, carbon ion radiotherapy. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 Outcomes of local control (LC) separated by T1 (A) or T2 (B) and individual prescribed doses for three groups: 28.0 to 34.0, 36.0 to 42.0, and 44.0 to 50.0 Gy (relative biological effectiveness [RBE]). Abbreviation: CIRT, carbon ion radiotherapy. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

5 Figure 4 Local control (LC) after carbon ion radiotherapy (CIRT) for tumor size (T1a, T1b, T2a, and T2b) in patients receiving 44.0 to 50.0 Gy (relative biological effectiveness [RBE]). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions


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