1. Smallpox Vaccine Logistics: Distribution, Storage and Security
WVDHHR/BPH
US Department of Health and Human Services
Centers for Disease Control and Prevention
December 2002 / January 2003

2. Smallpox Vaccine Logistics: Distribution, Storage and Security
Learning Objectives:
Describe how the smallpox vaccine will be ordered and shipped
Describe the support to be provided by the National Pharmaceutical Stockpile
Describe the storage and handling requirements for the smallpox vaccine

3. National Pharmaceutical Stockpile (NPS) Concept of Operations
Provide rapid delivery of a broad spectrum of support for an ill-defined threat in the early hours of an event
Provide large shipments of specific material when a threat is known
Provide technical assistance to receive and distribute NPS material during an event

4. NPS Response Options Broad Spectrum Support: Specific Item Support:
12-hour Push Packages
Specific Item Support:
Vendor Managed Inventory (VMI)
Vaccines
Buying Power/Surge Capacity

5. Distribution
Vaccine is a licensed product and all ancillary support will be in the kit
Each kit provides the capability to inoculate persons
In actual use, getting doses from each vial (kit).

6. What Do the Shipments Contain?
Vaccine
Diluents for vaccines that must be reconstituted (1 vial per every vial of vaccine)
Bifurcated needles
Transfer needles (1 needle for every vial of diluent)
Package insert
Lot number stickers

7. What Needs to be Acquired Locally
Non-latex gloves
Waterless hand cleanser
Chux pad
2 X 2 gauze pads, plus cloth tape or paper tape
Semi-permeable bandages
Needle (21G or smaller)

8. What Needs to be Acquired Locally
Zip lock plastic bags (to provide vaccinated persons with a supply of gauze pads, tape and bandages)
Sharps containers
Medical waste bags
Bleach/spray bottle
NOTE: DO NOT procure/use alcohol or alcohol wipes as alcohol inactivates the vaccine

9. Vaccine Handling “Cold Chain” must be constant during distribution
Temperature logging is required to validate that ° F (2-8° C) was maintained during movement
Vaccine kits will be shipped in approved shipping containers with cold packs and temperature monitor
Temperature monitor must be read as soon as vaccine arrives

10. Vaccine Handling
West Virginia State Police have primary responsibility for security & transporting vaccine to local/regional sites
State Immunization Program staff will contact State Police for transportation of vaccine kits

11. Vaccine Handling Regional/local sites must designate
Point of Contact (primary & alternate)
Name, title, address, phone, fax & directions
Delivery Site address & directions
Number of vaccination doses needed
Desired delivery date of vaccine kits

12. Vaccine Handling “Cold Chain” must be constant during redistribution
Temperature logging is required to validate that ° F (2-8° C) was maintained during movement
Temperature monitor must be checked as soon as vaccine arrives

13. Storage All kits must be maintained at 35 - 46° F (2-8° C)
Proper refrigeration must be in place at point of delivery
A temperature reading log must be maintained on the refrigeration system
Check/record storage temperature at least 2 times per day

14. Security Issues Code of Federal Regulations must be followed (21CFR)
Fixed storage facilities
Controlled access to both facility and the storage system
Surveillance (video) and/or security staff

15. Reminders Vaccine should NEVER be frozen
Normal storage temperature is ° F (2-8° C)
AFTER reconstitution, vaccine:
Must be used within 60 days
Maintained at ° F (2-8° C)

16. For More Information West Virginia Immunization Program
Jeff Neccuzi, Program Manager OR

17. National Pharmaceutical Stockpile
For More Information
National Pharmaceutical Stockpile
Telephone:

18. For More Information CDC Smallpox website www.cdc.gov/smallpox
National Immunization Program website