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Lymphocyte Phenotype during Therapy for Acute Graft-versus-Host Disease: A Brief Report from BMT-CTN 0302  Javier Bolaños-Meade, Juan Wu, Brent R. Logan,

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Presentation on theme: "Lymphocyte Phenotype during Therapy for Acute Graft-versus-Host Disease: A Brief Report from BMT-CTN 0302  Javier Bolaños-Meade, Juan Wu, Brent R. Logan,"— Presentation transcript:

1 Lymphocyte Phenotype during Therapy for Acute Graft-versus-Host Disease: A Brief Report from BMT-CTN 0302  Javier Bolaños-Meade, Juan Wu, Brent R. Logan, John E. Levine, Vincent T. Ho, Amin M. Alousi, Daniel J. Weisdorf, Leo Luznik  Biology of Blood and Marrow Transplantation  Volume 19, Issue 3, Pages (March 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Boxplot of CD45+ cell counts for day 28 GVHD responders versus nonresponders. The P value reflects the CD45+ cell count change from baseline to day 28 posttreatment for day 28 responders versus nonresponders. Data are on a log scale, with a 1-unit change equal to +10 and a 2-unit change equal to +100. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Cumulative incidence of cGVHD by day 14 CD8+ lymphocyte count. The P value reflects a comparison of the cumulative incidence of cGVHD for patients with higher CD8+ counts (cells ≥100/μL; n = 50) at day 14 versus patients with lower CD8+ counts (cells <100/μL; n = 46) at day 14. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 OS by day 14 CD45+ lymphocyte count. The P value reflects a comparison of OS probability for patients with higher CD45+ cell counts (cells ≥200/μL; n = 41) at day 14 versus patients with lower CD45+ cell counts (cells <200/μL; n = 34) at day 14. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions


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