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First Finite Element Model of the Left Ventricle With Mitral Valve: Insights Into Ischemic Mitral Regurgitation  Jonathan F. Wenk, PhD, Zhihong Zhang,

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Presentation on theme: "First Finite Element Model of the Left Ventricle With Mitral Valve: Insights Into Ischemic Mitral Regurgitation  Jonathan F. Wenk, PhD, Zhihong Zhang,"— Presentation transcript:

1 First Finite Element Model of the Left Ventricle With Mitral Valve: Insights Into Ischemic Mitral Regurgitation  Jonathan F. Wenk, PhD, Zhihong Zhang, MS, Guangming Cheng, MD, PhD, Deepak Malhotra, MD, Gabriel Acevedo-Bolton, PhD, Mike Burger, MS, Takamaro Suzuki, MD, David A. Saloner, PhD, Arthur W. Wallace, MD, PhD, Julius M. Guccione, PhD, Mark B. Ratcliffe, MD  The Annals of Thoracic Surgery  Volume 89, Issue 5, Pages (May 2010) DOI: /j.athoracsur Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) Short-axis and (B) long-axis magnetic resonance imaging slices with contour lines. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Surface geometry developed in Rapidform. (A) Epicardial contour lines (imported from FindTags) and surface and (B) mitral valve leaflet and annulus contour lines (imported from Find Contours), along with the IGES surface (IGES is an internationally accepted standard protocol for transferring the information of a two-dimensional or three-dimensional model between different CAD/CAM software). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Finite element model in the undeformed configuration. (A) Exterior view of the left ventricle showing posterobasal myocardial infarction. (B) Interior view of the left ventricle with chordae connected to the papillary muscles. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Mitral valve in the undeformed configuration. (A) Atrial view of the mitral valve with coordinate system defined. (B) The underside of the mitral valve showing the chordal insertion points. Note the edge chordae attachments along the free edge and the strut chordae attachments at the midsection of the leaflets. The anterior leaflet is green and yellow, and the posterior leaflet is blue. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Echocardiograph image of a sheep with 2+ mitral regurgitation, where the blue region indicates the regurgitant jet. (LA = left atrium; LV = left ventricle.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 (A) Oblique view of mitral valve deformation at end-diastole, wall elements have been hidden. (B) Oblique view of mitral valve deformation at end-systole, with close up view of the gap. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

8 Fig 7 Overlay of stiff infarct model (wire mesh) and soft infarct model (solid) at end-systole. (A) Short axis slice. (B) Long axis slice. The white arrow indicates the location of the posterior papillary muscle. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

9 Fig 8 Overlay of stiff infarct model (wire mesh) and soft infarct model (solid) at end-systole, with a close-up view of the gap between the mitral valve leaflets. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions


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