1. Numerous protumorigenic proteins are largely unaltered by obesity.
Numerous protumorigenic proteins are largely unaltered by obesity. Banked human serum was obtained from sarcoma subjects and healthy donors. Quantitative analyte expression of serum samples was analyzed by Luminex-based assays for human cancer biomarker, cytokines and chemokines. Analytes were then analyzed according to BMI grouping (normal weight ≤24.9 kg/m2; overweight = 25–29.9 kg/m2; obese ≥30 kg/m2) for (A) sarcoma subjects alone or (B) healthy controls alone. Gaussian distribution was assessed using the D’Agostino–Pearson omnibus normality (p > 0.05 threshold). Statistical significance was determined by an ordinary one-way ANOVA with post hoc Tukey multiple comparisons test (as denoted by asterisks; *) or by Kruskal–Wallis test with post hoc Dunn multiple comparisons test (as denoted by number/pound signs; #). *,#p < 0.05.
Claire M. Buchta et al. ImmunoHorizons 2017;1:20-28
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