1. Pharmacological effects of intravenous melatonin: comparative studies with thiopental and propofol 
M. Naguib, D.L. Hammond, P.G. Schmid III, M.T. Baker, J. Cutkomp, L. Queral, T. Smith 
British Journal of Anaesthesia 
Volume 90, Issue 4, Pages (April 2003)
DOI: /bja/aeg092
Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
Cumulative log dose–response curves for melatonin, propofol, thiopental and their vehicles for (a) loss of response to 60 mm Hg paw pressure and (b) loss of righting reflex (n=7–10 rats). Con=vehicle. Dose–effect curves were generated with data obtained 1 min after drug administration. (c) Time course of the effect of bolus injection of equipotent doses (ED95 for the loss of righting reflex) of thiopental 23.8 mg kg–1, propofol 14.9 mg kg–1 or melatonin 312 mg kg–1 or their vehicles on mean arterial pressure (n=7 rats in each group). *P<0.05 vs the respective vehicle.
British Journal of Anaesthesia  , DOI: ( /bja/aeg092)
Copyright © 2003 British Journal of Anaesthesia Terms and Conditions