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Combined Submyeloablative and Myeloablative Dose Intense Melphalan Results in Satisfactory Responses with Acceptable Toxicity in Patients with Multiple.

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Presentation on theme: "Combined Submyeloablative and Myeloablative Dose Intense Melphalan Results in Satisfactory Responses with Acceptable Toxicity in Patients with Multiple."— Presentation transcript:

1 Combined Submyeloablative and Myeloablative Dose Intense Melphalan Results in Satisfactory Responses with Acceptable Toxicity in Patients with Multiple Myeloma  Nicolas Novitzky, Jaqueline Thomson, Valda Thomas, Cecile du Toit, Zainab Mohamed, Andrew McDonald  Biology of Blood and Marrow Transplantation  Volume 16, Issue 10, Pages (October 2010) DOI: /j.bbmt Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Graphical representation of the laboratory parameters and of Karnofsky scores at the different stages of the described therapeutic strategy. All the values are significantly different from the presentation parameters. (Dexa: dexamethasone; SCT 1 and 2: stem cell transplant 1 and 2). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 OS of the study population. (A) Shows the overall outcome. (B) Shows the outcome according to type of response to the therapeutic strategy. Patients who failed to achieve at least VGPR had significantly worse outcome. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions


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