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Preoperative Angiotensin-Converting Enzyme Inhibitors and Acute Kidney Injury After Coronary Artery Bypass Grafting  Umberto Benedetto, MD, Sebastiano.

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Presentation on theme: "Preoperative Angiotensin-Converting Enzyme Inhibitors and Acute Kidney Injury After Coronary Artery Bypass Grafting  Umberto Benedetto, MD, Sebastiano."— Presentation transcript:

1 Preoperative Angiotensin-Converting Enzyme Inhibitors and Acute Kidney Injury After Coronary Artery Bypass Grafting  Umberto Benedetto, MD, Sebastiano Sciarretta, MD, Antonino Roscitano, MD, Brenno Fiorani, MD, Simone Refice, MD, Emiliano Angeloni, MD, Riccardo Sinatra, MD  The Annals of Thoracic Surgery  Volume 86, Issue 4, Pages (October 2008) DOI: /j.athoracsur Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Prediction curvesa for acute kidney injury (AKI) for patients who received angiotensin-converting enzyme (ACE) inhibitorsb (dashed line) and patients who did not receive ACE inhibitors preoperativelyc (solid line). The comparative predictive curves for AKI in two groups showed that a beneficial effect of preoperative ACE inhibitors was achieved for all preoperative value of glomerular filtration rate (GFR). (aModel definition: Y = a + b × log(x). bAdjusted coefficient of multiple regression Ra2 = 0.50; cAdjusted coefficient of multiple regression Ra2 = 0.36.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

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