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Early Aortic Bioprosthetic Valve Deterioration in an Octogenarian

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Presentation on theme: "Early Aortic Bioprosthetic Valve Deterioration in an Octogenarian"— Presentation transcript:

1 Early Aortic Bioprosthetic Valve Deterioration in an Octogenarian
Hironori Izutani, MD, PhD, Takanori Shibukawa, MD, Jun Kawamoto, MD, Shingo Mochiduki, MD, Dairoku Nishikawa, MD  The Annals of Thoracic Surgery  Volume 86, Issue 4, Pages (October 2008) DOI: /j.athoracsur Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Echocardiographic images of the aortic Perimount valve (Edwards Lifesciences, Irvine, CA) at diastolic phase (A) and systolic phase (B) showed bioprosthetic valve dysfunction with leaflet stiffness and motion restriction (arrows). There was severe aortic stenosis with a maximum flow of 4.6 m/sec (a maximum pressure gradient of 83 mm Hg) and an aortic valve area of 0.27 cm2. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Autopsy findings of the explanted Perimount valve (Edwards Lifesciences, Irvine, CA) viewing from (A) outflow and (B) inflow. Gross examination revealed that the three leaflets were stiff with restricted motion, and the valve was stenotic. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Microscopic examination of the explanted Perimount valve (Edwards Lifesciences, Irvine, CA) leaflet showed calcification deposits (intrinsic calcification) into the leaflet without inflammatory reaction. (Hematoxylin and eosin; ×100). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

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