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Volume 25, Issue 1, Pages 5-7 (January 2017)

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1 Volume 25, Issue 1, Pages 5-7 (January 2017)
Orchestrating a Symphony on a Single Conjugate: Aptamer Targeting, Gene Silencing, and Immunomodulation to Enhance Antitumor Response  Brandon D. Ng, Dan Peer  Molecular Therapy  Volume 25, Issue 1, Pages 5-7 (January 2017) DOI: /j.ymthe Copyright © 2017 The American Society of Gene and Cell Therapy Terms and Conditions

2 Figure 1 CD8+ T Cell Differentiation Mediated by the 4-1BB Aptamer-CD25 siRNA Conjugate Upper path (with aptamer-siRNA conjugate) shows differentiation into MPECs, while the lower path (without aptamer-siRNA conjugate) shows differentiation into SLECs and eventual apoptosis. Molecular Therapy  , 5-7DOI: ( /j.ymthe ) Copyright © 2017 The American Society of Gene and Cell Therapy Terms and Conditions


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