1. Development of Dendritic-Cell Lineages
Li Wu, Yong-Jun Liu 
Immunity 
Volume 26, Issue 6, Pages (June 2007)
DOI: /j.immuni
Copyright © 2007 Elsevier Inc. Terms and Conditions

2. Figure 1
A Developmental Scheme of Mouse DC Development from BM Hemopoietic Stem Cells and Lineage-Committed Progenitors
Both cDC and pDC can be generated from the Flt3 expressing early myeloid or lymphoid progenitors. Flt3L is essential for the development of steady-state DC populations. Under inflammatory conditions, i.e., in the presence of GM-CSF, monocytes can differentiate into cDC. Abbreviations: HSC, hemopoietic stem cell; MPP, multipotent progenitors; CMP, common myeloid precursors; CLP, common lymphoid precursors; GMP, granulocyte and macrophage precursors; MEP, megakaryocyte and erythrocyte precursors; M-DC, macrophage and DC precursors.
Immunity  , DOI: ( /j.immuni )
Copyright © 2007 Elsevier Inc. Terms and Conditions