1. Predicting arterial blood gas and lactate from central venous blood analysis in critically ill patients: a multicentre, prospective, diagnostic accuracy study 
T. Boulain, D. Garot, P. Vignon, J.-B. Lascarrou, D. Benzekri-Lefevre, P.-F. Dequin 
British Journal of Anaesthesia 
Volume 117, Issue 3, Pages (September 2016)
DOI: /bja/aew261
Copyright © 2016 The Author(s) Terms and Conditions

2. Fig 1 Flow diagram. ICU, intensive care unit.
British Journal of Anaesthesia  , DOI: ( /bja/aew261)
Copyright © 2016 The Author(s) Terms and Conditions

3. Fig 2
Performance of model for predicting arterial partial pressure of carbon dioxide ( P a C O 2 ). This figure plots predicted arterial partial pressure of carbon dioxide   ( pred P a C O 2 ) vs actual P a C O 2 values in our validation set. Vertical dashed lines indicate the ‘optimal’ cut-off value of   pred P a C O 2 that yielded the highest positive likelihood ratio (LHR) associated with an upper limit of 95% confidence interval of the negative LHR below 0.1 (as determined from our derivation set). Horizontal dashed lines indicate the threshold of P a C O 2 to be predicted. Vertical and horizontal lines delineate four quadrants showing the number of true-positive (TP), true-negative (TN), false-positive (FP), and false-negative (FN) events. (a) Repartition of TP, TN, FP, and FN events with the   pred P a C O 2 cut-off of 5.0 kPa to detect P a C O 2 <4.6 kPa. (b) Repartition of TP, TN, FP, and FN events with the   pred P a C O 2 cut-off of 5.5 kPa to detect P a C O 2 >6.0 kPa. (We considered that the range of 4.6–6.0 kPa for P a C O 2 was the normal range.)
British Journal of Anaesthesia  , DOI: ( /bja/aew261)
Copyright © 2016 The Author(s) Terms and Conditions

4. Fig 3
Performance of model for predicting arterial oxygen saturation ( S a O 2 ). This figure plots predicted S a O 2 (   pred S a O 2 , using the simpler model, i.e. not using clinical characteristics) vs actual S a O 2 values in our validation set. The vertical dashed line indicates the best cut-off value (as determined from our derivation set) of   pred S a O 2 to predict an actual S a O 2 < 90 % . Th ehorizontal dashed line indicates the threshold of S a O 2 to be predicted. Vertical and horizontal lines delineate four quadrants showing the number of true-positive (TP), true-negative (TN), false-positive (FP), and false-negative (FN) events.
British Journal of Anaesthesia  , DOI: ( /bja/aew261)
Copyright © 2016 The Author(s) Terms and Conditions