1. 1 http://www.usrf.org USRF20021992 A California non-profit organization

2. 2 http://www.usrf.org USRF20021992 What is USRF? URSF is an independent, non-profit organization (501c3) founded in 1992 to further the science of urology. Funding Funding -Gifts -Grants -Contracts Governance Governance -Founder -Board of Directors

3. 3 http://www.usrf.org USRF20021992 What is USRF? MISSION STATEMENT: To help advance the understanding of common urologic disorders and, through relationships with innovative leaders in the healthcare industry, to perform important clinical trials.

4. 4 http://www.usrf.org USRF20021992 Who are we ? Key to Productivity: 2002 USRF Staff

5. 5 http://www.usrf.org USRF20021992 Diplomate, American Board of Urology Diplomate, American Board of Urology Clinical faculty, UCLA Clinical faculty, UCLA Associate editor, Urology Associate editor, Urology Committee member, AUA Committee member, AUA Founder and Medical Director Leonard S. Marks, M.D.

6. 6 http://www.usrf.org USRF20021992 L.A. Metropolitan Location Population: 16 Million (2nd largest metropolitan area in U.S.) USRF Offices

7. 7 http://www.usrf.org USRF20021992 USRF Offices USRF Saw Palmetto Study: Lead Story in Urology Times

8. 8 http://www.usrf.org USRF20021992 USRF Offices Updating the USRF Website

9. 9 http://www.usrf.org USRF20021992 Economy Economy Efficiency Efficiency -Large patient base -Established practice USRF offers industry... Mannekin Pis

10. 10 http://www.usrf.org USRF20021992 Experience Experience -28 trials -Various aspects of research Dedicated space and personnel Dedicated space and personnel -Well-trained staff -Fully-equipped office USRF offers industry... Mannekin Pis

11. 11 http://www.usrf.org USRF20021992 Knowledge of industry Knowledge of industry -Consultancies -Study designs Academic involvement Academic involvement -Presentations -Publications USRF offers industry... Mannekin Pis

12. 12 http://www.usrf.org USRF20021992 USRF Focus Areas Prostate Diseases Prostate Diseases -Benign -Malignant Impotency (MED) Impotency (MED) Incontinence Incontinence -Male -Female

13. 13 http://www.usrf.org USRF20021992 Recent Industry Sponsors Alza Alza Endocare Endocare Diagnostic Ultrasound Diagnostic Ultrasound Glaxo-Wellcome Glaxo-Wellcome Hybritech Hybritech Merck Merck Nutrilite Nutrilite Pfizer Pfizer Pharmacia & Upjohn Pharmacia & Upjohn Synthelabo Synthelabo

14. 14 http://www.usrf.org USRF20021992 Recent Clinical Trials (Phase I - IV)

15. 15 http://www.usrf.org USRF20021992 Recent Clinical Trials (Phase I - IV) Devices Devices -Prostate stent -Laser -Vaporizing electrode -Ultrasound PSA Testing PSA Testing

16. 16 http://www.usrf.org USRF20021992 Academic Collaborations UCLA UCLA Johns Hopkins Johns Hopkins Mayo Clinic Mayo Clinic

17. 17 http://www.usrf.org USRF20021992 Educational Mission Dr. Marks lecturing in Mexico City, January 99

18. 18 http://www.usrf.org USRF20021992 USRF on WWW

19. 19 http://www.usrf.org USRF20021992 28 clinical trials 28 clinical trials -BPH -CaP -MED -Incontinence -Urinary Infection USRF History, 1992-2002

20. 20 http://www.usrf.org USRF20021992 17 sponsoring companies 17 sponsoring companies -Large and small -Drug and device -Repeat sponsors USRF History, 1992-2002

21. 21 http://www.usrf.org USRF20021992 18 publications in peer-reviewed journals 18 publications in peer-reviewed journals 30 papers presented at scientific meeting 30 papers presented at scientific meeting USRF History, 1992-2002

22. 22 http://www.usrf.org USRF20021992 4 university projects funded 4 university projects funded -UCLA (residents research fund) -Johns Hopkins (morphometry, MRI) -U. Maryland (apoptosis) -Oregon Health Sciences U. (androgen) USRF History, 1992-2002

23. 23 http://www.usrf.org USRF20021992 A California non-profit organization