1. Volume 117, Issue 4, Pages 831-837 (October 1999)
Mapping of a target region of allelic loss to a 0.5-cm interval on chromosome 22q13 in human colorectal cancer 
Antoni Castells, Yasushi Ino, David N. Louis, Vijaya Ramesh, James F. Gusella, Anil K. Rustgi 
Gastroenterology 
Volume 117, Issue 4, Pages (October 1999)
DOI: /S (99)
Copyright © 1999 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Deletion mapping of chromosome 22q. Markers appear on the linkage map (Genethon) and on the ideogram. Case numbers are shown above each map. ●, Allelic loss; ○, retention of both alleles. In noninformative loci, no circle is depicted. The smallest region of overlap is outlined by a rectangle superimposed on the maps.
Gastroenterology  , DOI: ( /S (99) )
Copyright © 1999 American Gastroenterological Association Terms and Conditions

3. Fig. 2
DNA polymorphism analysis. Autoradiograms corresponding to the microsatellite loci limiting the region of deletion in 2 cases with partial losses. For cases 6 and 67, D22S1171 shows retention of both alleles and D22S1140 exhibits allelic loss, thus delimiting the centromeric boundary. For case 73, D22S1140 exhibits allelic loss and D22S928 retention of both alleles, thus delimiting the telomeric boundary. N and T, nontumoral and tumoral DNA samples, respectively. Arrowhead corresponds to the position of the deleted allele.
Gastroenterology  , DOI: ( /S (99) )
Copyright © 1999 American Gastroenterological Association Terms and Conditions

4. Fig. 3
A graphical representation of the NBK/BIK gene structure. Exons are represented by rectangles and labeled with the nucleotide position according to the complementary DNA sequence (accession no. U34584). Shaded regions correspond to untranslated regions. Patterned region in exon 3 corresponds to the BCL-2 homology domain BH3. Introns are not to scale.
Gastroenterology  , DOI: ( /S (99) )
Copyright © 1999 American Gastroenterological Association Terms and Conditions