1. Familial Aggregation of Insulin Resistance in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease 
Manal F. Abdelmalek, Chen Liu, Jonathan Shuster, David R. Nelson, Nabih R. Asal 
Clinical Gastroenterology and Hepatology 
Volume 4, Issue 9, Pages (September 2006)
DOI: /j.cgh
Copyright © 2006 American Gastroenterological Association Terms and Conditions

2. Figure 1
Kindred 1 pedigree. The mother of a 40-year-old woman with a histologic diagnosis of NASH died at age 68 of complications related to cirrhosis. Both grandparents died at an advanced age of cardiovascular disease. □, male; ○, female; ↑, alive; ↓, dead.
Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh )
Copyright © 2006 American Gastroenterological Association Terms and Conditions

3. Figure 2
Kindred 2 pedigree. The index case is a 53-year-old man with confirmed NASH. His mother and grandmother had unexplained cirrhosis but no history of alcohol consumption. The maternal diagnosis of cirrhosis and steatohepatitis was confirmed at autopsy. The patient’s brother was reported to have an asymptomatic increase of liver enzyme levels during routine health screening but died of suicide. cva, cerebral vascular accident; mi, myocardial infarction. □, male; ○, female; ↑, alive; ↓, dead.
Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh )
Copyright © 2006 American Gastroenterological Association Terms and Conditions

4. Figure 3
Kindred 3 pedigree. Pedigree chart shows a strong maternal or gender-dominant expression of NASH in the index patient, with both the mother and grandmother having a diagnosis of cryptogenic cirrhosis. □, male; ○, female; ↑, alive; ↓, dead.
Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh )
Copyright © 2006 American Gastroenterological Association Terms and Conditions