1. Ascorbate, Blood-Brain Barrier Function and Acute Mountain Sickness: A Radical Hypothesis 
Damian Miles Bailey, PhD 
Wilderness & Environmental Medicine 
Volume 15, Issue 3, Pages (September 2004)
DOI: / (2004)15[234:LTTE]2.0.CO;2
Copyright © 2004 Wilderness Medical Society Terms and Conditions

2. Effects of l-ascorbic acid supplementation on the redox status of human blood (n=1). Resting blood samples were obtained before (pre-bolus) and 1.5 hours after (post-bolus) oral ingestion of 6×50mg l-ascorbic acid (phase 1). The same protocol was repeated after 7 days of l-ascorbic acid supplementation at a dose of 6×50 mg/d (phase 2). Blank spectra based on degassed toluene+α-phenyl-tert-butylnitrone (PBN) or dimethylsulfoxide only (excludes human serum). Axes for all respective ordinates are identically scaled. Note that the increase in ascorbate concentration (directly proportional to the amplitude of dimethylsulfoxide-A·-spectral peaks) was associated with a parallel decrease in PBN adduct concentration.
Wilderness & Environmental Medicine  , DOI: ( / (2004)15[234:LTTE]2.0.CO;2)
Copyright © 2004 Wilderness Medical Society Terms and Conditions