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Utility of age-specific serum anti-Müllerian hormone concentrations

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Presentation on theme: "Utility of age-specific serum anti-Müllerian hormone concentrations"— Presentation transcript:

1 Utility of age-specific serum anti-Müllerian hormone concentrations
David H. Barad, Andrea Weghofer, Norbert Gleicher  Reproductive BioMedicine Online  Volume 22, Issue 3, Pages (March 2011) DOI: /j.rbmo Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Age-specific anti-Müllerian hormone (AMH) and FSH concentrations relating to age of 792 women with FSH <12mIU/ml and oestradiol ⩽80pg/ml. Values are means and 95% CI. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 Definition of age-specific anti-Müllerian hormone (AMH) relating to age of 792 women with FSH <12mIU/ml and oestradiol ⩽80pg/ml. Values are median (lines), 25–75th centile (boxes) and 95% CI (whiskers). AMH concentrations declined significantly with age (P<0.001). Table 2 summarizes lower and upper cutoff values at various ages. Circles=outliers; stars=extreme outliers. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

4 Figure 3 Oocyte yields at different ages and anti-Müllerian hormone (AMH) concentrations. (A) Oocyte yields among 442 women who underwent IVF with normal and high AMH (green) and abnormally low AMH (blue); ∗Significant differences within each age group are based on the Mann Whitney U-test (P<0.05). (B) Oocyte yields in each age group based on abnormally low (blue), normal (green) and abnormally high (beige) as-AMH concentrations. Normal was defined as within the 25–75th centiles for a given age group; ∗Significant differences from normal within each age group (P<0.05). Table 3 gives further statistical details. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions


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