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Volume 91, Issue 2, Pages (February 2017)

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Presentation on theme: "Volume 91, Issue 2, Pages (February 2017)"— Presentation transcript:

1 Volume 91, Issue 2, Pages 263-264 (February 2017)
Journal Club  Kidney International  Volume 91, Issue 2, Pages (February 2017) DOI: /j.kint Copyright © 2016 International Society of Nephrology Terms and Conditions

2 Schematic presentation of the role of Gli1+ adventitial mesenchymal stem cells in atherogenesis and vascular calcification. Gli1+ adventitial mesenchymal stem cell–like cells are vascular smooth muscle cell progenitors. After arterial injury, Gli1+ cells contribute to neointima formation and arterial repair. Gli1+ adventitial cells form osteoblast-like cells during vascular calcification. Genetic ablation of Gli1+ cells before injury abolishes vascular calcification. VSMCs, vascular smooth muscle cells. Reprinted from Kramann R, Goettsch C, Wongboonsin J, et al. Adventitial cells transform into osteoblast-like cells and drive vascular calcification in chronic kidney disease. Cell Stem Cell. 2016; 19: 628–642; © 2016, by permission from Elsevier. Kidney International  , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions

3 Royal free hospital cirrhosis glomerular filtration rate
Royal free hospital cirrhosis glomerular filtration rate. GFR, glomerular filtration rate; INR, international normalized ratio. Reprinted from Kalafateli M, Wickham F, Burniston M, et al. Development and validation of a mathematical equation to estimate glomerular filtration rate in cirrhosis: the royal free hospital cirrhosis glomerular filtration rate [e-pub ahead of print]. Hepatology. © 2016, by permission from the American Association for the Study of Liver Diseases. Kidney International  , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions


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