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Elevated serum cystatin C level is an independent predictor of contrast-induced nephropathy and adverse outcomes in patients with peripheral artery disease undergoing endovascular therapy Gwang-Sil Kim, MD, Young-Guk Ko, MD, Dong-Ho Shin, MD, PhD, Jung-Sun Kim, MD, PhD, Byeong-Keuk Kim, MD, PhD, Donghoon Choi, MD, PhD, Myeong-Ki Hong, MD, PhD, Yangsoo Jang, MD, PhD Journal of Vascular Surgery Volume 61, Issue 5, Pages (May 2015) DOI: /j.jvs Copyright © 2015 Society for Vascular Surgery Terms and Conditions
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Fig 1 Receiver operating characteristic (ROC) curve to detect contrast-induced nephropathy (CIN) using initial level of cystatin C, creatinine (Cr), Cr-based glomerular filtration rate (GFR), and cystatin C-based GFR. AUC, Area under the curve; CI, confidence interval; SE, standard error. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions
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Fig 2 Predictive value of baseline cystatin C (A) and creatinine (B) in subgroup analysis. BMI, Body mass index; CI, confidence interval; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HTN, hypertension. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions
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Fig 3 Kaplan-Meier survival curves showing occurrence of clinical events during follow-up period depending on cystatin C quartile. Q, Quartile; TVR, target vessel revascularization. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions
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Fig 4 Kaplan-Meier survival curves comparing major adverse event-free survivals of the patient subsets with baseline cystatin C level ≥1.35 mg/L vs cystatin C level <1.35 mg/L (A) and of the patient subsets with vs without contrast-induced nephropathy (CIN, B). Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions
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