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Genomewide Scan for Nonsyndromic Cleft Lip and Palate in Multigenerational Indian Families Reveals Significant Evidence of Linkage at 13q Uppala Radhakrishna, Uppala Ratnamala, Mathew Gaines, Soraya Beiraghi, David Hutchings, Jeffrey Golla, Syed A. Husain, Prakash S. Gambhir, Jayesh J. Sheth, Frenny J. Sheth, Ghati K. Chetan, Mohammed Naveed, Jitendra V. Solanki, Uday C. Patel, Dilipkumar C. Master, Rafiq Memon, Gregory S. Antonarakis, Stylianos E. Antonarakis, Swapan K. Nath The American Journal of Human Genetics Volume 79, Issue 3, Pages (September 2006) DOI: /507487 Copyright © 2006 The American Society of Human Genetics Terms and Conditions
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Figure 1 Partial pedigrees of families UR017 and UR019 with CL-P. Affected individuals are shown with blackened symbols, and unaffected individuals are shown with unblackened symbols. Data are not available for deceased individuals shown with a question mark. Samples included in the analysis are numbered under their symbols in the pedigree. The American Journal of Human Genetics , DOI: ( /507487) Copyright © 2006 The American Society of Human Genetics Terms and Conditions
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Figure 2 Partial pedigrees of UR017 and UR019, with genotypes and haplotypes of chromosome 13q. SNP markers are shown below selected individuals. Haplotypes associated with affected status are shown in red. Haplotype analysis indicated that the cosegregating segment of the CL-P locus is flanked proximally by rs and distally by rs on chromosome 13q The American Journal of Human Genetics , DOI: ( /507487) Copyright © 2006 The American Society of Human Genetics Terms and Conditions
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