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Interactions of cytokines, growth factors, and the extracellular matrix in the cellular biology of uterine leiomyomata  Ibrahim Sozen, M.D., Aydin Arici,

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Presentation on theme: "Interactions of cytokines, growth factors, and the extracellular matrix in the cellular biology of uterine leiomyomata  Ibrahim Sozen, M.D., Aydin Arici,"— Presentation transcript:

1 Interactions of cytokines, growth factors, and the extracellular matrix in the cellular biology of uterine leiomyomata  Ibrahim Sozen, M.D., Aydin Arici, M.D.  Fertility and Sterility  Volume 78, Issue 1, Pages 1-12 (July 2002) DOI: /S (02)

2 FIGURE 1 A model for pathogenesis of leiomyoma at the cellular level, integrating the most likely causative growth factor TGF-β and the chemokine MCP-1. (A), Interactions between MCP-1, TGF-β, and GnRH-a. (B), Interactions between TGF-β, GnRH=a, MMPs, and TIMPs. Sozen. Cellular biology of leiomyoma. Fertil Steril 2002. Fertility and Sterility  , 1-12DOI: ( /S (02) )


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