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Corneodesmosomal Water Content in Frozen-Hydrated Porcine Skin

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Presentation on theme: "Corneodesmosomal Water Content in Frozen-Hydrated Porcine Skin"— Presentation transcript:

1 Corneodesmosomal Water Content in Frozen-Hydrated Porcine Skin
Emre Firlar, Matthew Libera, Hilal Ilarslan, Manoj Misra  Journal of Investigative Dermatology  Volume 135, Issue 6, Pages (June 2015) DOI: /jid Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Corneodesmosomes (CDs) are enriched in water. (a) Phase–contrast image of three neighboring corneocytes (C), C from lower SC showing CDs and lipid-rich regions (L), scale bar=50nm. (b) Higher-magnification phase–contrast image of area used for water mapping. Scale bar=100nm. (c) Water map (12nm × 12nm pixel size) corresponding to the area in b. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 The water concentration fluctuates within individual corneodesmosomes (CDs). (a) Profiles of water concentration across six different CDs. (b) Phase–contrast image of a CD. (c) fluctuations in image intensity (from the rectangular region in b) correlate inversely with the average water profile (from a) across a CD. Scale bar=50nm. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions


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